Labordiagnostische Referenzbereiche bei unterschiedlichen Schweinerassen sowie histopathologische und immunhistochemische Untersuchung von Gehirnen älterer Sauen und Eber auf transmissible spongiforme Enzephalopathie im Rahmen der TSE-Studie
Beschreibung
vor 21 Jahren
The aim of the present study was to make a statement about selected
blood ingredients for twelve pig breeds regarding the influence of
the genotype. A possible race-dependence was proved for
haematological parameters especially for erythrocytes, thrombocytes
and leucocytes. Differences between the breeds were also found for
electrolytes and the trace elements although a statement concerning
breed-specifity was more difficult because some other environmental
factors can have strong influence on these parameters as well. In
part clear differences, which are caused by different physical
characteristics and attributes of the animals such as muscle mass
and susceptibility to stress, were established for substrates and
enzymes. We were able to show that the pietrain pigs possess a
remarkably higher concentration of some blood ingredients, in
comparison with “German Landrace and Edelschwein“. To conclude, the
results show, that there are marked differences in characteristics.
We detected a varying influence of the genotype on the
hematological and chemical blood parameters. The varying
concentration of the blood parameters in the examined breeds seems
to result from breed-specific metabolism and resistance to
infections and environmental influence. The immune-histochemical
search for accumulation of pathological prion protein with the
antibody L42 in 48 brain tissue sections of both sows and boars was
negativ. Nonetheless, it is possible to experimentally infect pigs
with the infectious prion protein from cattle. This means that, in
spite of the species-barrier, even though the infection was
transmitted parenterally, pigs, along with many other animals, are
susceptible to an infection with the bse-agent. There is a definite
need for acquiring further knowledge on the exact onset of and
events during infection and on the degree of contagiousness of
transmissible spongiform encephalopathy not only in swine.
blood ingredients for twelve pig breeds regarding the influence of
the genotype. A possible race-dependence was proved for
haematological parameters especially for erythrocytes, thrombocytes
and leucocytes. Differences between the breeds were also found for
electrolytes and the trace elements although a statement concerning
breed-specifity was more difficult because some other environmental
factors can have strong influence on these parameters as well. In
part clear differences, which are caused by different physical
characteristics and attributes of the animals such as muscle mass
and susceptibility to stress, were established for substrates and
enzymes. We were able to show that the pietrain pigs possess a
remarkably higher concentration of some blood ingredients, in
comparison with “German Landrace and Edelschwein“. To conclude, the
results show, that there are marked differences in characteristics.
We detected a varying influence of the genotype on the
hematological and chemical blood parameters. The varying
concentration of the blood parameters in the examined breeds seems
to result from breed-specific metabolism and resistance to
infections and environmental influence. The immune-histochemical
search for accumulation of pathological prion protein with the
antibody L42 in 48 brain tissue sections of both sows and boars was
negativ. Nonetheless, it is possible to experimentally infect pigs
with the infectious prion protein from cattle. This means that, in
spite of the species-barrier, even though the infection was
transmitted parenterally, pigs, along with many other animals, are
susceptible to an infection with the bse-agent. There is a definite
need for acquiring further knowledge on the exact onset of and
events during infection and on the degree of contagiousness of
transmissible spongiform encephalopathy not only in swine.
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