TWiV 1244: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent
Racaniello discusses Vijay Prasad’s return to the FDA, revoking
of COVID vaccine authorization for young children, the
Legionnaires’ outbreak in Harlem, the new labeling requirements
for Ixchiq, the infectious attenuated Chikungunya vaccine and the
importation of H5 influenza virus in Antarctica, before Dr.
Griffin deep dives into recent statistics on RSV, influenza and
SARS-CoV-2 infections, the Wasterwater Scan dashboard, guidelines
for treating COVID-19, whether or not the NB.1.8.1 should be
included in the fall 2025 vaccines, where to find PEMGARDA, long
COVID treatment center, where to go for answers to your long
COVID questions, the association of “virus rebound” and
post-acute sequelae among hospitalized patients, how virus
infection particularly influenza and SARS-CoV-2 may ‘re-activate’
dormant cancer cells and contacting your federal government
representative to stop the assault on science and biomedical
research.


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Links for this episode

Prasad returns to the FDA
(Washington Post)

Pfizer Covid vaccine for young children may not
be renewed by FDA (The Guardian)

Report suggests FDA may not reauthorize Pfizer COVID vaccine
for young kids (CIDRAP)

Factors Associated With Pediatric COVID-19 Mortality: A
Pediatric Investigators Collaborative Network on Infections in
Canada (PICNIC) Study (Journal of Pediatric
Infectious Diseases Society)


Legionnaires’ Disease: In Harlem (NYC Health)

Recommended Pause in Use of Ixchiq (Chikungunya
Vaccine, Live) in Individuals 60 Years of Age and
Older While Postmarketing Safety Reports are Investigated (FDA)

FDA Removes Recommended Pause in Use
and Approves Required Updated Labeling
(FDA)


Chikungunya Vaccines (CDC: Chikungunya
virus)


Chikungunya in China (CDC: Travelers’
Health)

Travelers’ health notices (CDC:
Travelers’ Health)


Areas at Risk for Chikungunya (CDC:
Chikungunya virus)

Adjuvanted recombinant zoster
vaccine is effective against herpes zoster
ophthalmicus, and is associated with lower risk of acute
myocardial infarction and stroke in adults aged ≥50 years (CID)

Tracking HPAIV H5 through a geographic survey
of Antarctic seabird populations

(Scientific Reports)

Report details first suspected H5 avian
flu detections in seabirds in Antarctica(CIDRAP)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)


Measles (CDC Measles (Rubeola))

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts(ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)


FDA-CDC-DOD: 2025-2046 influenza vaccine
composition (FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

ENFLONSIA: novel
drug approvals 2025 (FDA)

RSV-Network (CDC Respiratory Syncytial virus
Infection)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

2025 Clinical Practice Guideline Update by the Infectious
Diseases Society of America on the Treatment and
Management of COVID-19: Pemivibart for Pre-exposure
Prophylaxis, Vilobelimab for Critical Illness, and Abatacept or
Infliximab for Severe or Critical Illness (CID)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)


Where to get pemgarda (Pemgarda)


EUA for the pre-exposure
prophylaxis of COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)


Paxlovid (Pfizer)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)

Steroids,dexamethasone at the right
time (OFID)


Anticoagulation guidelines
(hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

TWiV 1243: Capitalism, COVID and
Cancer (MicrobeTV)

Respiratory viral
infections awaken metastatic breast
cancer cells in lungs(Nature)

Reaching out to US house representative


Letters read on TWiV 1244

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.