TWiV 1294: Clinical update with Dr. Daniel Griffin

In his weekly clinical update during Ground hog week, Dr. Griffin
and Vincent Racaniello are back to discuss the measles outbreak
in South Carolina, American Academy of Pediatrics vaccine
recommendations and shingles vaccine and the reduction of
dementia, then deep dives into recent statistics RSV, influenza
and SARS-CoV-2 infections, the Wastewater Scan dashboard, Johns
Hopkins measles tracker, where to find PEMGARDA, how to access
and pay for Paxlovid, estimated effectiveness of this year’s
COVID-19 vaccine, long COVID treatment center, where to go for
answers to your long COVID questions, long COVID in children, the
potential benefits of metformin to reduce disease severity
following SARS-CoV-2 infection in obese and overweight patients
and contacting your federal government representative to stop the
assault on science and biomedical research.


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Links for this episode

Grading the groundhogs (National
Oceanic and Atmospheric Administration)

Sand Mountain Sam predicts an early
spring (News19)

All About the AAP
Recommended Immunization Schedule
(healthychildren.org)


Recommended Childhood and Adolescent
Immunization Schedule: United States, 2026: Policy Statement
(American Academy of Pediatrics: Pediatrics)

Herpes zoster vaccination and
incident dementia in Canada: an
analysis of natural experiments (LANCET: Neurology)

Detection of avian flu antibodies in Dutch dairy
cow: ECDC risk assessment remains unchanged (European
Centre for Disease Prevention and Control)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Big outbreak, bright lights…Measles
Dashboard(South Carolina Department of Public Health)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles(CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts (ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)


OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

USrespiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Estimated Effectiveness of
2024-2025 COVID-19 Vaccination Against Severe COVID-19 (JAMA)


Where to get pemgarda (Pemgarda)


EUA for the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

Understanding Coverage Options
(PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Long COVID associated with
SARS-CoV-2 reinfection among children
and adolescents in the omicron era (RECOVER-EHR): a retrospective
cohort study (LANCET: Infectious Diseases)

Long COVID is here to stay—even in
children (LANCET: Infectious Diseases)


Early administration of neutralising
monoclonal antibodies and post-acute sequelae of COVID-19
(International Journal of Infectious Diseases)

Preventing Long COVID
With Metformin (CID)

Metformin may reduce risk of long
COVID by 64% in overweight or obese adults

(CIDRAP)

Effect of Metformin on the Risk of Post-coronavirus Disease
2019 Condition Among Individuals With Overweight or
Obese (CID)


Preventing Long COVID With Metformin
(CID)

New review highlights growing
evidence that diabetes drug metformin can prevent long COVID
(CIDRAP)

Reaching out to US house representative


Letters read on TWiV 1294

Dr. Griffin's COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.