TWiV 1248: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent
Racaniello are dismayed about the recent attack on public health
the firing of the director of the CDC as well as resignation of 3
others members of the agency’s leadership, the continued
Legionnaire’s outbreak in Harlem, suspension of Ixchiq the
Chikungunya virus attenuated infectious vaccine, the first US
case of New World screwworm before Dr. Griffin deep dives into
recent statistics on the measles epidemic, RSV, influenza and
SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns
Hopkins measles tracker, association Guillian-Barré syndrome with
RSV vaccination, guidelines for using RSV vaccines, whether or
not the NB.1.8.1 should be included in the fall 2025 vaccines,
the American College Obstetricians and Gynecologists
recommendations for the COVID, RSV and influenza vaccines, FDA
approval letters for Pfizer, moderna and Novagax COVID vaccines
including label changes for use in those between 5 through 64
years, where to find PEMGARDA, long COVID treatment center, where
to go for answers to your long COVID questions, and contacting
your federal government representative to stop the assault on
science and biomedical research.


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Links for this episode

White House Says New C.D.C. Director Is
Fired, but She Refuses to Leave (NY Times)

CDC director refuses to
leave after White House order (BBC)


Legionnaires’ Disease: In Harlem(NYC
Health)

New York City Health Department Provides Update
on Community Cluster of Legionnaires’
Disease in Central Harlem(NYC Health: Promoting and protecting
the City’s health)

FDA Update on the Safety of
Ixchiq (Chikungunya Vaccine,
Live) (FDA)


Vimkunya (Bavarian Nordiac)

U.S. and Panama for the control of the Screwworm
pest (COPEG)

Rare human case of flesh-eating
parasite New World screwworm identified in US(CNN)

USDA Announces Sweeping Plans to Protect the
United States from New World Screwworm (USDA)

HHS details New World
screwworm response after human case(CIDRAP)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)


Measles (CDC Measles (Rubeola))

Measles vaccine recommendations from NYP
(jpg)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts(ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)

Relative effectiveness of high-dose versus
standard-dose influenza vaccine against
hospitalizations and mortality according to frailty score (JID)


FDA-CDC-DOD: 2025-2046 influenza vaccine
composition (FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

ENFLONSIA: novel
drug approvals 2025 (FDA)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))

Evaluation of Guillain-Barré Syndrome
(GBS) following Respiratory Syncytial Virus (RSV)
Vaccination Among Adults 65 Years and Older (FDA)


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)

Evidence
to Recommendations Framework
(EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National
Center for Immunization and Respiratory Diseases)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)

Veering from CDC, ACOG
recommends maternal vaccination against COVID-19
(CIDRAP)

ACOG Releases Updated Maternal Immunization
Guidance for COVID-19, Influenza, and RSV (American
College of Obstericians and Gynecologists)

COVID-19 Vaccination Considerations
for Obstetric–Gynecologic
Care (American College of Obstericians and
Gynecologists)

Pfizer and BioNTech’s COMIRNATY Receives U.S.
FDA Approval for Adults 65 and Older and
Individuals Ages 5 through 64 at Increased Risk for Severe
COVID-19 (Pfizer)

 COMIRNATY approval letter (FDA)

Moderna Receives U.S. FDA Approval for Updated
COVID-19 Vaccines Targeting LP.8.1 Variant of
SARS-CoV-2 (FEEDS)


SPIKEVAX approval letter (FDA)

Novavax’s Nuvaxovid
2025-2026 Formula COVID-19 Vaccine Approved in the
U.S (Novavax)

NUVAXOVID approval letter (FDA)


Where to get pemgarda (Pemgarda)


EUA for the pre-exposure
prophylaxis of COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)


Paxlovid (Pfizer)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)

Steroids,dexamethasone at the right
time (OFID)


Anticoagulation guidelines
(hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Reaching out to US house representative


Letters read on TWiV 1248

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.