TWiV 1252: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent
Racaniello discuss the continued Legionnaire’s outbreak in
Harlem, invasive Asia longhorned tick and associated disease,
potential Ebola outbreak in the Congo, Florida ending childhood
vaccine mandates, before Dr. Griffin deep dives into recent
statistics on the measles epidemic, RSV, influenza and SARS-CoV-2
infections, the Wasterwater Scan dashboard, Johns Hopkins measles
tracker, SARS-CoV-2 spillover into household/domestic dogs, real
data demonstrating the benefits of COVID-19 vaccines, states that
increase access to COVID-19 vaccines, effective and availability
to PAXLOVID, where to find PEMGARDA, long COVID treatment center,
where to go for answers to your long COVID questions, the
beginning of numerous long COVID clinical studies and contacting
your federal government representative to stop the assault on
science and biomedical research.


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Links for this episode


Legionnaires’ Disease: In Harlem (NYC
Health)

2 dead, dozens sickened by Legionnaires’
disease in Westchester County: Officials (NBC News)


Invasive longhorned tick found for 1st
time in New England (AP News)

First person bitten by east Asian longhorned
tick (AP News)

Invasive, disease-carrying
tick found in Maine, the farthest northeast it has
been spotted (AP News)

Suspected cases rise in DR Congo
Ebola outbreak (CIDRAP)


Ebola in the Democratic Republic of the
Congo (CDC: Travelers’ Health)

 Patricia Mazzei (NY Times)

Florida Moves to End Vaccine
Mandates for Schoolchildren (NY Times)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)


Measles (CDC Measles (Rubeola))

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts (ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)


Influenza-Associated Hospitalizations During
a High Severity Season — Influenza Hospitalization Surveillance
Network, United States, 2024–25 Influenza Season (CDC: MMWR)

US respiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)

Influenza Vaccine Composition for
the 2025-2026 U.S. Influenza Season
(FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)

Risk factors for severe
outcomes of respiratory syncytial virus infection
in children (LANCET: Regional Health Europe)

US respiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)

Evidence
to Recommendations Framework
(EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National
Center for Immunization and Respiratory Diseases)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)

Spillover of SARS-CoV-2 to domestic
dogs in COVID-19–positive households: A one health
surveillance study (Virus Research)

Pfizer and BioNTech Announce Topline
Data Demonstrating Robust Immune Response With
Their LP.8.1-Adapted COVID-19 Vaccine 2025-2026 Formula
 (Pfizer)


Minnesota, New York issue executive
orders promoting access to COVID vaccines (CIDRAP)

No. 52: Declaring a Disaster in
the State of New York Due to Federal Actions Related to Vaccine
Access(NY State: Executive Order #52)


Where to get pemgarda (Pemgarda)


EUA for the pre-exposure
prophylaxis of COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)

Patient-Reported Outcomes of
Nirmatrelvir Treatment for High-Risk, Nonhospitalized Adults With
Symptomatic COVID-19 (OFID)

Real-world effectiveness of
nirmatrelvir-ritonavir against severe outcomes of COVID-19 in
Taiwan (OFID)

PAXLOVID-nirmatrelvir and ritonavir : highlights
of prescribing information
(Pfizer)

Help your eligible patients access
PAXLOVID with the PAXCESS Patient Support Program
(Pfizer)

PAXCESSTM offers access and
affordability options to patients
prescribed PAXLOVIDTM (nirmatrelvir tablets; ritonavir
tablets) (PAXCESS)

Steroids,dexamethasone at the right
time (OFID)


Anticoagulation guidelines
(hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Clinical trials explore how Low-Dose
Naltrexone could help people with Long COVID (The
Sick Times)


Three clinical trials for Long COVID are
testing JAK inhibitors to treat immune dysregulation (The Sick
Times)

Research updates, July 29: Stellate ganglion
blocks, may help reduce the severity of some symptoms of
Long COVID and ME  (The Sick Times)

New Long COVID and complex disease center at
Mount Sinai set to be a leader in research,
clinical care (The Sick Times)

RECOVER-TLC announces new Long COVID clinical
trials, receives mixed reactions from patient community
(The Sick Times)

Reaching out to US house representative


Letters read on TWiV 1252

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.