TWiV 1275: An amazing sequence and a gutsy therapy

TWiV explains the Nobel Prize-winning discovery of pre-mRNA
splicing, and engineering bacteriophage to deliver proteins to
the human intestine.


Hosts: Vincent Racaniello, Kathy Spindler,
and Brianne Barker


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Links for this episode

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Immune 100 live at the Incubator

Spliced segments of adenovirus mRNA (PNAS)

An amazing sequence in adenovirus mRNA (Cell)

Nobel Prize for mRNA splicing (Nobel)

A predominant undecanucleotide in adenovirus late
mRNAs (Cell)

Splicing RNA with Phillip A. Sharp (ASM)

Protein production in the gut by engineered
phage (Nat Biotech)

Engineered phage T4 (Curr Op Virol)

Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Brianne – Can You Identify These Lines
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Kathy – Saturday Morning Physics,
Photograph 51 and JCE article
Rich – Wikipedia:Wiki Science
Competition 2025 in the United States
Jolene – Data visualization
workshop
Vincent – Transformer: The Deep
Chemistry of Life and Death by Nick Lane


Intro music is by Ronald Jenkees


Send your virology questions and comments to twiv@microbe.tv


Content in this podcast should not be construed as medical
advice.