TWiV 1278: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello
discuss the rise in norovirus infections, contamination of infant
formula and botulism outbreak, confusion and response to the
CDC’s ACIP decision to reverse the recommendation for a birth
dose of the hepatis B virus vaccine and how states in the
Northwest and Northeast are responding as well as some insurance
companies, then deep dives into recent statistics on the measles
epidemic, RSV, influenza and SARS-CoV-2 infections, the
Wasterwater Scan dashboard, Johns Hopkins measles tracker, South
Carolina’s imposed quarantine of individuals due to their
accelerated measles outbreak, neurotropism of H1N1, benefits of
the RSV and COVID vaccines, where to find PEMGARDA, how to access
and pay for Paxlovid, long COVID treatment center, where to go
for answers to your long COVID questions, and contacting your
federal government representative to stop the assault on science
and biomedical research.


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Links for this episode

Norovirus season! (Wastewater Scan)

Outbreak Investigation of Infant
Botulism: Infant Formula (November 2025) (FDA: Foodborne
illnesses)

Botulism outbreak sickens more than 50 babies and expands
to all ByHeart products (AP News)

CDC advisers drop
decades-old universal hepatitis B birth dose
recommendation, suggest blood testing after 1 dose (CIDRAP)


Health and Economic Benefits of Routine
Childhood Immunizations in the Era of the Vaccines for Children
Program — United States, 1994–2023 (CDC: MMWR)

Universal Hepatitis B vaccination at
birth: safety, effectiveness and public health impact
(CIDRAP)


Recommended Child and Adolescent
Immunization Schedule for Ages 18 years or
younger (American Academy of Pediatrics)

West Coast health experts reject RFK Jr.
panel, say hepatitis B vaccines at birth should continue
(The Oregonian)

Statement from the Northeast Public Health
Collaborative In Response to ACIP’s Hepatitis B
Vote (NJ.Gov Health)

Governors Denounce ACIP
Recommendation on Hepatitis B Vaccination, Reaffirm
Commitment to Strong, Evidence-Based Childhood Vaccination
Programs (Governors Public Health Alliance)


Blue Cross and Blue Shield Companies
Statement on Vaccines (Blue Cross Blue Shield)


AHIPStatement on Vaccine Coverage (AHIP)

Pediatricians reject CDC advisers’ guidance, plan
to continue vaccinating all
newborns against hepatitis B (CIDRAP)

Survey: Social media on par
with CDC as trusted vaccine source
(Healio)


FDA to investigate whether adult deaths
linked to COVID vaccine (Washington Post)

Exclusive: US FDA launches fresh safety
scrutiny of approved RSV therapies for infants
(Reuters)

Marburg Outbreak in Ethiopia: Current
Situation (CDC: Marburg Virus Disease)

Contemporary highly pathogenic avian influenza (H5N1)
viruses retain neurotropism in human
cerebral organoids (OFID)

Confirmations of Highly Pathogenic Avian
Influenza in Commercial and Backyard
Flocks (USDA: Animal and Plant Health Inspection
Service)

Indiana, cases of New
World screwworm in Mexico, rising US flu activity

(CIDRAP)

Mexico reports 92 cases of myiasis
in humans caused by screwworm (Expreso.press)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts(ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Hundreds quarantined as South Carolina measles
outbreak accelerates (Washington Post)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

USrespiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)


ACIP Recommendations Summary (CDC:
Influenza)


Types of Influenza Viruses (CDC:
Influenza (flu))

Influenza Vaccine Composition for
the 2025-2026 U.S. Influenza Season
(FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

USrespiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)

Intensive Care Unit Stay and Mechanical Ventilation
Among Adults with Respiratory Syncytial
Virus-Related Hospitalization by Age and
Comorbidity Status (Infectious Diseases and Therapy)

Cardiovascular Events 1 Year After
Respiratory Syncytial Virus Infection in Adults (JAMA: Open
Network)


Long-Term Illness in Adults Hospitalized
for Respiratory Syncytial Virus Disease, United States,
February 2022–September 2023 (CDC: Emerging Infectious
Diseases)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))

Effectiveness of the maternal RSVpreF
vaccine against severe disease in infants in
Scotland, UK: a national, population-based case–control study and
cohort analysis (LANCET: Infectious Diseases)

Effectiveness of Nirsevimab in Preventing
Respiratory Syncytial Virus-related Burden: A
Test-negative Case-control Study in Infants With Bronchiolitis in
Lombardy Region, Italy (The Pediatric Infectious Disease Journal)


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)


Maternal and Neonatal Outcomes After
Respiratory Syncytial Virus Prefusion F Protein Vaccination
During Pregnancy (Obstetrics & Gynecology)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)

COVID-19 mRNA Vaccination and 4-Year All-Cause
Mortality Among Adults Aged 18 to 59 Years in
France (JAMA: Open Network)


Two-year prognosis of mRNA
vaccine-related myocarditis compared with historical
conventional myocarditis: a population-based cohort study (CMI:
Clinical Microbiology and Infection)


Where to get pemgarda (Pemgarda)


EUAfor the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

UnderstandingCoverageOptions (PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID Reaching out
to US house representative


Letters read on TWiV 1278

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.