TWiV 1280: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello
protest Vinjay Prasad, head of CBER FDA Nov memo stating
administration of the COVID-19 vaccine resulted in 10 children’s
deaths, but are cautiously delighted by the December memo from
those in CBER who dispute this data-less claim, how in 31 states
pertussis vaccination rates have declined before Dr. Griffin then
deep dives into recent statistics on the measles epidemic, RSV,
influenza and SARS-CoV-2 infections, the Wasterwater Scan
dashboard, Johns Hopkins measles tracker, of clinical outcomes of
oseltamivir versus baloxavir for treating influenza infection,
number deaths associated with COVID-19 hospitalizations and
disease associated economic burden, where to find PEMGARDA, how
to access and pay for Paxlovid, long COVID treatment center,
where to go for answers to your long COVID questions, how the
German government is committed to research into long COVID and
contacting your federal government representative to stop the
assault on science and biomedical research.


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Links for this episode

Industry laments Prasad vaccine
memo (Politico)

Scoop: FDA vaccine chief’s memo cited 10 pediatric Covid-19
vaccine deaths—but the agency’s own analysis found
0–7 (Inside Medicine)

Whooping cough cases soar as vaccination rates
drop (NBC News)

Marburg Outbreak in Ethiopia: Current
Situation (CDC: Marburg Virus Disease)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles(CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts (ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Hundreds quarantined as South Carolina measles
outbreak accelerates (Washington Post)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

USrespiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)

In call with clinicians, CDC
recommends flu vaccines widely (CIDRAP)

Influenza Vaccine Composition for
the 2025-2026 U.S. Influenza Season
(FDA)

Comparison of clinical outcomes of oseltamivir
versus baloxavir in outpatients with influenza: a
retrospective cohort analysis (International Journal of
Infectious Diseases)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

USrespiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)

Effectiveness of 2024–2025 COVID-19 Vaccines in
Children in the United States — VISION, August 29,
2024–September 2, 2025 (CDC:MMWR)


Mortality following recovery from
COVID-19 hospitalization: A long-term cohort study
(International Journal of Infectious Diseases)


COVID hospitalization tied to 69% higher
risk of death for up to 2 years (CIDRAP)


Where to get pemgarda (Pemgarda)


EUAfor the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

Understanding Coverage Options
(PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Comparison of work productivity losses in the United States
among employees with COVID-19 at high-risk of severe disease who
were untreated or treated with
nirmatrelvir/ritonavir (Journal of Medical Economics)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Long-COVID research just got a big funding
boost: will it find new treatments?(Nature)

Reaching out to US house representative


Letters read on TWiV 1280

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.