TWiV 1282: Clinical update with Dr. Daniel Griffin

Calling out “Happy Christmas to all and to all a
good-night,  Dr. Griffin and Vincent Racaniello discuss high
path influenza in dairy herds in Wisconsin and Marburg virus in
Ethiopia before Dr. Griffin then deep dives into recent
statistics on the measles epidemic, RSV, influenza and SARS-CoV-2
infections, the Wasterwater Scan dashboard, Johns Hopkins measles
tracker, the slightly higher association of COVID-19 infection
with death than following influenza infection, benefit of passive
infant immunization with niresevimab, association of COVID-19
vaccine immunogenicity protection against severe disease in
vulnerable populations, where to find PEMGARDA, how to access and
pay for Paxlovid, long COVID treatment center, effect of
remdesivir and nirmatrelvir/ritonavir on COVID-19 associated
mortality, where to go for answers to your long COVID questions,
and contacting your federal government representative to stop the
assault on science and biomedical research.


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Links for this episode

USDA Confirms Highly Pathogenic Avian Influenza in a
Dairy Herd in Wisconsin

(USDA Animal and Plant Health Inspection Service)

Update: Genetic Sequencing
Results for Wisconsin Dairy Herd Detection of
Highly Pathogenic Avian Influenza(USDA Animal and Plant Health
Inspection Service)

Marburg Outbreak in Ethiopia: Current
Situation (CDC: Marburg Virus Disease)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles(CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts (ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

USrespiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)

In call with clinicians, CDC
recommends flu vaccines widely(CIDRAP)

Influenza Vaccine Composition for
the 2025-2026 U.S. Influenza Season
(FDA)

Increased 30-day Mortality Risk in
Coronavirus Disease 2019 Compared to Seasonal Influenza
(International Journal of Infectious Diseases)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

USrespiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)


Nirsevimab vs RSVpreF Vaccine for
Respiratory Syncytial Virus–Related Hospitalization in Newborns
(JAMA)

RSV Immunization Frequently
Asked Questions(American Academy of Pediatrics)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)

Association between COVID-19 vaccine
immunogenicity and protection against infection and
severe disease in clinically vulnerable patient populations: a
systematic review and meta-analysis of observational studies
(Clinical Microbiology and Infection)


Where to get pemgarda (Pemgarda)


EUAfor the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

Understanding Coverage Options
(PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

The effect of remdesivir and
nirmatrelvir/ritonavir on mortality in patients
hospitalized with COVID-19 during the Omicron era: an emulated
target trial (Clinical Microbiology and Infection)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Long-COVID research just got a big funding
boost: will it find new treatments? (Nature) Reaching
out to US house representative


Letters read on TWiV 1282

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.