TWiV 1284: Clinical update with Dr. Daniel Griffin

Recording after the ball drops, Dr. Griffin and Vincent
Racaniello wish everyone a Happy New Year, discuss an
evidence-based approach to teaching and practice medicine and
reminisce on the history of vaccine development and use before
their discussion about the whooping cough outbreak of 2025 in the
US and falling levels of tetanus vaccination, then Dr. Griffin
then deep dives into recent statistics on the measles epidemic,
RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan
dashboard, Johns Hopkins measles tracker, how NY state reported
the greatest number of influenza confirmed infections ever in one
week during the week ending Dec 20,  where to find PEMGARDA,
how to access and pay for Paxlovid, long COVID treatment center,
where to go for answers to your long COVID questions, and
contacting your federal government representative to stop the
assault on science and biomedical research.


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Links for this episode


Evidence-Based Medicine: A New Approach
to Teaching the Practice of Medicine (JAMA)

The US has seen nearly 28,000 whooping cough
cases this year. Here’s what you need to know (CNN)

Vaccine History: Developments by
Year (CHOP, Children’s hospital of Philadelphia:
Vaccine History)

Reported Incidence of notable
diseases in United States: 1952 Morbidity and
Mortality Weekly Report, Vol. 1, No. 54, October 26, 1953 (CDC:
Stacks)

As tetanus vaccination rates decline,
doctors worry about rising case numbers (nbc News)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts(ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

New York State Department of Health
Confirms Most Flu Cases Ever Recorded in One
Week: New York State Reports 71,123 Flu Cases This Week
(NY State Department of Health)

Weekly surveillance report: cliff
notes (CDC FluView)

Influenza Vaccine Composition for
the 2025-2026 U.S. Influenza Season
(FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)


Nirsevimab vs RSVpreF Vaccine for
Respiratory Syncytial Virus–Related Hospitalization in Newborns
(JAMA)

RSV Immunization Frequently
Asked Questions(American Academy of Pediatrics)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)


Where to get pemgarda (Pemgarda)


EUAfor the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

UnderstandingCoverageOptions (PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Reaching out to US house representative


Letters read on TWiV 1284

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.