TWiV 1288: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello
are bewildered and dismayed by RFK Jr’s announced changes in the
routine childhood immunization schedule, though not unpredicted,
and highlight the science and evidence which eviscerate these
changes, then deep dives into recent statistics on the measles
epidemic- in particular in South Carolina, RSV, influenza and
SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns
Hopkins measles tracker, estimated societal burden of COVID-19
illness, deaths and hospitalizations, benefit of maternal
COVID-19 vaccination, where to find PEMGARDA, how to access and
pay for Paxlovid, long COVID treatment center, where to go for
answers to your long COVID questions, neurodevelopmental
consequences of in-utero SARS-CoV-2 infection and contacting your
federal government representative to stop the assault on science
and biomedical research.


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Links for this episode

7 great Danish cheeses you should
know (Cheese Professor)


Norovirus in on the rise! (WasterWater
Scan)


Maternal Vaccine Receipt and Infant
Hospital and Emergency Visits for Influenza and
Pertussis (JAMA Open)

TUESDAY MEASLES UPDATE: DPH Reports 124 New
Measles Cases in Upstate, New Public Exposures, and
Upcoming Vaccination Opportunities (South Carolina: Department of
Public Health-they have one?)

Measles cases soar in South Carolina,
top 400 (CIDRAP)


Wastewater for measles (WasterWater Scan)

Measles cases and outbreaks (CDC
Rubeola)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Measles vaccine recommendations from NYP
(jpg)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts (ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

USrespiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: cliff
notes (CDC FluView)

North Dakota confirms pediatric flu
deaths as some states note surge in flu activity
(CIDRAP)


OPTION 2: XOFLUZA $50 Cash Pay Option
(Xofluza)

The Best Flu Drug Americans Aren’t
Taking (The Atlantic)

Influenza Vaccine Composition for
the 2025-2026 U.S. Influenza
Season(FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

Impact of universal nirsevimab
prophylaxis in infants on hospital and primary care
outcomes across two respiratory syncytial virus seasons in
Galicia, Spain (NIRSE-GAL): a population-based prospective
observational study (Lancet: Infectious Diseases)

Interim Safety of RSVpreF
Vaccination During Pregnancy (JAMA)

Pfizer’s RSV vaccine safe to use
during pregnancy, study suggests (CIDRAP)

USrespiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virus Infection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Antigenic and Virological Characteristics of SARS-CoV-2
Variant BA.3.2, XFG, and
NB.1.8.1 (bioRxiV)

Evaluating the Effectiveness of 2024–2025
Seasonal mRNA-1273 Vaccination Against
COVID-19-Related Hospitalizations and Medically Attended COVID-19
Among Adults Aged ≥ 18 years in the United States:
An Observational Matched Cohort Study (Infectious Diseases and
Therapy)


Where to get pemgarda (Pemgarda)


EUAfor the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

UnderstandingCoverageOptions (PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

Use of corticosteroids in
influenza-associated acute respiratory distress
syndrome and severe pneumonia: a systemic review and
meta-analysis(Scientific Reports)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID

Incidence and Severity of Postacute Sequelae of
SARS-CoV-2 Infection in the Omicron Era: A
Prospective Cohort Study (JID)

Reaching out to US house representative


Letters read on TWiV 1288

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.