TWiV 1290: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello
discuss screwworm, how the shingles vaccination slows biological
aging (for all of you who want to reset ‘the clock’ and live
forever…..you know who you are Musk, Bezos) and getting one dose
of the HPV vaccine, then Dr. Griffin then deep dives into recent
statistics on RSV, influenza and SARS-CoV-2 infections, the
Wasterwater Scan dashboard, Johns Hopkins measles tracker, how
losing our elimination status is the cost of doing business
(going for broke is never a good business model !) where to find
PEMGARDA, how to access and pay for Paxlovid, long COVID
treatment center, the effectiveness of this season’s influenza
vaccine, where to go for answers to your long COVID questions and
contacting your federal government representative to stop the
assault on science and biomedical research.


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Links for this episode

New World Screwworm: Outbreak Moves into Northern
Mexico……with an official tag “This is an official
CDC Health Advisory” (CDC: Health Alert Network)

Association between shingles vaccination andslower
biological aging: Evidence from a U.S. population-based
cohort study (The Journals of Gerontology series A)

Noninferiority of One HPV Vaccine
Dose to Two Doses (NEJM)


Herd effect of human papillomavirus
vaccination on incidence of high-grade cervical lesions:
(LANCET: Public Health)

Confirmations of Highly Pathogenic Avian Influenza
in Commercial and Backyard
Flocks (USDA: Animal and Plant Health Inspection
Service)

Detections of Highly Pathogenic Avian Influenza
in Wild Birds (USDA: Animal and Plant
Health Inspection Service)

Delaware, Georgia see major
commercial avian flu outbreaks (CIDRAP)


Wastewater for measles (WasterWater Scan)

Notes from the Field: Wastewater Surveillance
for Measles Virus During a Measles
Outbreak — Colorado, August 2025 (CDC: MMWR)

Notes from the Field: Retrospective Analysis of Wild-Type
Measles Virus in Wastewater During a Measles
Outbreak — Oregon, March 24–September 22, 2024
(CDC: MMWR)

Measles cases and outbreaks (CDC
Rubeola)

Measles vaccine recommendations from NYP
(jpg)

Tracking Measles Cases in the U.S.
(Johns Hopkins)

Utah measles total rises to 216; CDC deputy director says
losing elimination status‘cost of doing
business’ (CIDRAP)


Weekly measles and rubella monitoring
(Government of Canada)


Measles (WHO)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)

Adverse events associated with childhood
vaccines: evidence bearing on causality (NLM)

Measles Vaccination: Know the
Facts (ISDA: Infectious Diseases Society of America)

Deaths following vaccination: what does
the evidence show (Vaccine)

Assessing MMR vaccination coverage
gaps in US children with digital participatory
surveillance (Nature Health)

Influenza: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

Respiratory virus activity levels
(CDC Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)

Effectiveness of influenza vaccination
to prevent severe disease: a systematic
review and meta-analysis of test-negative design studies (CMI:
Clinical Microbiology and Infection)


Interim vaccine effectiveness against
influenza virus among outpatients, France, October 2025 to
January 2026 (Eurosurveillance)

Moderate protection from vaccination against influenza
A(H3N2) subclade K in Beijing, China,
September to December 2025 (Eurosurviellance)

Current flu vaccine provides moderate
protection against severe disease, interim analyses
suggest (CIDRAP)


OPTION 2: XOFLUZA $50 Cash Pay Option
(xofluza)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)


Respiratory Diseases (Yale School of
Public Health)

USrespiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)


Vaccines for Adults (CDC: Respiratory
Syncytial Virusnfection (RSV))


Economic Analysis of Protein Subunit and
mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

Respiratory Illnesses Data
Channel (CDC: Respiratory Illnesses)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)


Where to get pemgarda (Pemgarda)


EUAfor the pre-exposure prophylaxis of
COVID-19 (INVIYD)

Infusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)

Drug
interaction checker (University of
Liverpool)

Help your eligible patients
access PAXLOVID with the PAXCESS Patient Support
Program (Pfizer Pro)

UnderstandingCoverageOptions (PAXCESS)


Infectious Disease Society guidelines for
treatment and management (ID Society)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

Managing healthcare
staffing shortages (CDC)


Anticoagulationguidelines (hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID Reaching out
to US house representative


Letters read on TWiV 1290

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.