Inside the New Era of Precision Medicine: Where AI and Human Insight Unite

Medicine stands at the threshold of a new era, where artificial
intelligence and systems biology are working hand in hand to make
care more personal, predictive, and precise than ever before. AI is
already improving diagnostic accuracy, automating administrative
tasks, and uncovering patterns in data—like retinal scans or
genomics—that humans often miss. Rather than replacing doctors, AI
enhances their ability to deliver more informed, precise, and
efficient care. At the same time, individuals are gaining
tools—from at-home diagnostics to wearable biosensors—that empower
them to track and optimize their own health. This shift marks a
move from reactive, disease-centered care to a proactive,
data-driven model of scientific wellness. In this episode, I talk
with Dr. Eric Topol, Dr. Nathan Price, Dr. Leroy Hood, Dr. Vijay
Pande, and Daisy Wolf about how artificial intelligence,
personalized data, and wearable technology are converging to
radically transform medicine. Dr. Eric Topol is Executive Vice
President of Scripps Research and founder/director of its
Translational Institute, recognized as one of the top 10 most cited
researchers in medicine with over 1,300 publications. A
cardiologist and author of several bestselling books on the future
of medicine, he leads major NIH grants in precision medicine and
shares cutting-edge biomedical insights through his Ground Truths
newsletter and podcast. Dr. Nathan Price is Chief Scientific
Officer at Thorne HealthTech, author of The Age of Scientific
Wellness, and a National Academy of Medicine Emerging Leader. He
also serves on the Board on Life Sciences for the National
Academies and is Affiliate Faculty in Bioengineering and Computer
Science at the University of Washington. Dr. Leroy Hood is CEO and
founder of Phenome Health, leading the Human Phenome Initiative to
sequence and track the health of one million people over 10 years.
A pioneer in systems biology and co-founder of 17 biotech
companies, he is a recipient of the Lasker Prize, Kyoto Prize, and
National Medal of Science. Dr. Vijay Pande is a General Partner at
Andreessen Horowitz and founder of a16z Bio + Health, managing over
$3 billion in life sciences and healthcare investments at the
intersection of biology and AI. An Adjunct Professor at Stanford,
he is known for his work in computational science, earning honors
like the DeLano Prize and a Guinness World Record for Folding@Home.
Daisy Wolf is an investing partner at Andreessen Horowitz,
specializing in healthcare AI, consumer health, and
healthcare-fintech innovation. She previously worked at Meta and in
various startups, holds a JD from Yale Law, an MBA from Stanford,
and a BA from Yale, and is based in New York City. This episode is
brought to you by BIOptimizers. Head to bioptimizers.com/hyman and
use code HYMAN10 to save 10%. Full-length episodes can be found
here: Can AI Fix Our Health and Our Healthcare System? The Next
Revolution In Medicine: Scientific Wellness, AI And Disease
Reversal The Future of Healthcare: The Role of AI and Technology