The Future of Medicine Is Energy: Dr. Martin Picard Explains

I’ve seen so many patients struggle with fatigue, brain fog, and
burnout, and this conversation gave me a new way of thinking about
why that happens and how to approach it. On this episode of The Dr.
Hyman Show, I’m joined by Dr. Martin Picard, a Columbia scientist
studying how energy flows through the body, and what that flow
means for how we think, feel, and age. We touch on a simple idea
that could reframe the way you understand your own energy, and how
your daily choices influence it over time. Catch the full
conversation on YouTube or listen wherever you get your podcasts.
We uncover: • Why your energy can feel “off” even when labs look
normal • What mitochondria communicate beyond just ATP production •
How stress, recovery, and sleep shift your cellular energy capacity
• Why individuality matters more than group averages in real life
health outcomes • The simple daily choices that build or drain
metabolic resilience over time At the end of the day, energy is the
foundation of how we show up in our lives, and we can influence it
more than we think. Resources on the blog: • Phenomics and the
Energy Resistance Principle  View Show Notes From This Episode
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order.Get 20% off HTB Immune Energy Chews at bigboldhealth.com and
use code DRMARK20. (0:00) Intro: Martin Picard (1:56) Metabolism,
Mental Health & Functional Med (6:00) Mitochondria’s Role in
Health (14:15) Food, Diet & Lifestyle Impacts (16:31)
Understanding Mitochondrial Functions (20:30) Communication &
Energy Transfer (24:22) Dr. Hyman’s Mitochondrial Story (26:23) The
Energy Resistance Principle (31:08) Energy Budgets, Compensation
& Exercise (38:47) Applying Energy Resistance (41:08) Fatigue,
Sleep & Mitochondria (43:02) Health Implications (47:38)
Measuring Function & Biomarkers (49:22) Dysfunction &
Health Impact (55:23) Inflammation & Cytokines (1:00:00)
Exercise & Flow State (1:01:21) Muscle Fatigue & Heart Pain
(1:03:20) Conditions & Mitochondrial Health (1:04:08) Rest
& Individualized Treatment (1:07:39) Clinical Assessments
(1:10:00) Stress Testing & Energy Flow (1:13:09) Lifestyle
Interventions (1:17:24) Mitoception & Awareness (1:20:08)
Future Clinical Practices (1:21:48) Keto Diet & Mental Health
(1:27:03) Energy Conservation in Illness (1:32:08) Stress,
Resilience & Sleep