400 Startups Building the Post-Web Economy, with Outlier Ventures Founder Jamie Burke

Lex chats with Jamie Burke - founder of Outlier Ventures, about
the current state and future of Web3, decentralized finance, and
the metaverse. Jamie highlights Outlier Ventures' impressive
growth, with a portfolio of around 400 startups, and discusses
successful projects like IOTA and Fetch.ai. The conversation
delves into the open metaverse, emphasizing the importance of
infrastructure and middleware in blending physical and digital
realities. Jamie also explores the transformative role of AI in
the metaverse and offers practical advice for entrepreneurs
navigating this rapidly evolving landscape.


 


Notable discussion points:


 


1.The “Post-Web” Is an Intent-Led Internet: Jamie Burke outlines
a shift from today’s attention-based web to an intent-driven
internet, powered by AI agents, Web3 infrastructure, and DePIN.
In this model, agents act on user intent, radically streamlining
interactions and replacing much of today’s web interface.


 


2. Web3 Will Be Run by Machines, Not People: Burke predicts that
autonomous agents—not humans—will become the primary users of
blockchains, making crypto “machine money.” As a result,
products, brands, and processes matter less, while incentive
systems and on-chain automation take center stage.


 


3. Founders Must Embrace Systems Thinking: In the Post-Web era,
survival depends on designing self-optimizing systems, not just
building products. Burke stresses that token engineering,
incentive design, and value flow mapping will define the next
generation of durable startups.


 


MENTIONED IN THE CONVERSATION


 


Topics: Web3, decentralized finance, metaverse, Open metaverse,
Post web, Outlier Ventures, IOTA, Fetch.ai, accelerator program,
AI, artificial intelligence, Agentic AI, agents, Web3, post-web,
digital economy, blockchain technology


 


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TIMESTAMPS


 


1’18: Outlier Ventures in 2025: From IOTA to Fetch.ai, Backing
the Infrastructure Behind Intelligent Web3


 


10’24: The Open Metaverse Revisited: Outlier’s Long-Game Bet on
Augmented Reality, Middleware, and AI-Driven Agents


 


26’01: FThe Post-Web Era: How AI Agents, Web3 Infrastructure, and
Delegation Will Redefine the Internet


 


35’57: From Attention to Intention: How AI Agents and Web3 Are
Flipping the Internet on Its Head


 


49’39: Surviving the Post-Web Paradigm: Why Founders Must Shift
from Startup Thinking to Systems Design


 


57’49: The channels used to connect with Jamie & learn more
about Outlier Ventures


Disclaimer here — this newsletter does not provide investment
advice and represents solely the views and opinions of FINTECH
BLUEPRINT LTD.


Contributors: Lex, Laurence, Matt, Farhad, Mike, Daniella


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