TWiV 1206: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello
lament about the continuing measles outbreak, whether or not the
measles outbreak was predicted, the FACTS about vaccination, high
pathogenic influenza, H5N1 contaminated raw pet food, children’s
deaths, before Dr. Griffin reviews recent statistics on RSV,
influenza and SARS-CoV-2 infections and vaccination schedules and
the efficacy of Moderna’s seasonal mRNA vaccine, societal burden
of COVID-19 and influenza, the FDA missed deadline for approving
Novovax COVID vaccine, the WasterwaterScan dashboard, where to
find PEMGARDA, provides information for Columbia University
Irving Medical Center’s long COVID treatment center, where to go
for answers to your long COVID questions, long COVID
interventions, and Canada’s long COVID dashboard.


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Links for this episode

CDC buried a measles forecast that
stressed the need for vaccinations….TRANSPARENCY? (Politico)

Measles cases and outbreaks (CDC
Rubeola)

Measles 159 in Texas…. (Texas Health
and Human Services)

2025 Measles outbreak
guidance (New Mexico Health)

Measles and
rubella weekly monitoring report
(Government of Canada)

Enhanced epidemiological summary Measles in
Ontario (Public Health Ontario)


Measles and rubella weekly monitoring
report (Government of Canada)

Enhanced epidemiological summary Measles in
Ontario (Public Health Ontario)

Measles exposures in
Ontario (Public Health Ontario)

Measles vaccine recommendations from NYP (jpg)

Get the FACTS about measles (NY
State Department of Health)


Measles (CDC Measles (Rubeola))


Measles vaccine (CDC Measles (Rubeola))


Presumptive evidence of measles immunity
(CDC)


Contraindications and precautions to
measles vaccination (CDC)


Measles (CDC Measles (Rubeola))


Raw cat food tests positive for H5N1
(CIDRAP)

Influenza: Waste water scan for 11
pathogens WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

Weekly surveillance report: clift
notes (CDC FluView)

Respiratory virus activity levels
(CDC Respiratory Illnesses)


FDA-CDC-DOD: 2025-2046 influenza vaccine
composition (FDA)

RSV: Waste water scan for 11
pathogens (WastewaterSCan)

US respiratory virus activity (CDC
Respiratory Illnesses)

RSV-Network (CDC Respiratory Syncytial virus
Infection)

Early impact of RSV vaccination in
older adults in England (Lancet)

Waste water scan for 11
pathogens (WastewaterSCan)

COVID-19 deaths (CDC)

COVID-19 national and
regional trends (CDC)

COVID-19 variant tracker (CDC)

SARS-CoV-2 genomes galore
(Nextstrain)

Evaluating the effectiveness of
2024-2025 seasonal
mRNA-1273 vaccination against covid-19-associated
hospitalizations and medically attended covid-19 among adults
aged ≥ 18 years in the united states(medRxiv)

Current Moderna vaccine 53%
effective against COVID
hospitalization?(CIDRAP)

Preliminary estimates of COVID-19
burden for 2024-2025 (CDC COVID-19)

Estimated range of annual burden of
flu in the US from 2010 – 2024 (CDC-flu burden)

US FDA missed the deadline for
decision on Novavax’s COVID-19 vaccine (Reuters)

Interim clinical considerations for use of
COVID-19 vaccines in the United States (CDC
Vaccines & Immunizations)


Where to get pemgarda (Pemgarda)


EUA for the pre-exposure
prophylaxis of COVID-19 (INVIYD)

Fusion center (Prime Fusions)


CDC Quarantine guidelines (CDC)


NIH COVID-19 treatment guidelines (NIH)


Metformin alleviates inflammatory
response and severity rate of COVID-19 infection in elderly
individuals(Scientific Reports)

Drug
interaction checker (University of
Liverpool)


Infectious Disease Society guidelines for
treatment and management (ID Society)


Cost-effectiveness analysis of
nirmatrelvir/ritonavir for high-risk individuals with
COVID-19….does this mean use the big button calculator? (OFID)

Molnupiravir safety and efficacy
(JMV)

Convalescent plasma recommendation
for immunocompromised (ID Society)

What to do when sick with a respiratory
virus (CDC)

When your healthcare provider
is infected/exposed with SARS-CoV-2
(CDC

Managing healthcare
staffing shortages (CDC)

Steroids, dexamethasone at the
right time (OFID)


Anticoagulation guidelines
(hematology.org)

Daniel Griffin’s evidence
based medical practices for long COVID (OFID)

Long COVID hotline (Columbia :
Columbia University Irving Medical Center)


The answers: Long COVID


Reinfection with SARS-CoV-2 in the
omicron era is associated with increased risk of post-acute
sequelae of SARS-CoV-2  infection: a recover-EHR cohort
study(medRxiv)


CAN-PCC RecMap, your one-stop shop for
recommendations about Post COVID-19 Condition (Long COVID)
(Canadian Guidelines for post COVID-19 condition)


Letters read on TWiV 1206

Dr. Griffin’s COVID treatment summary (pdf)

Timestamps by Jolene Ramsey. Thanks!



Intro music is by Ronald Jenkees


Send your questions for Dr. Griffin to daniel@microbe.tv


Content in this podcast should not be construed as medical
advice.