TWiV 1237: Hepatitis C and persistence with Charlie Rice

From the 2025 annual meeting of the American Society for
Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or
Medicine, talks with Vincent and Kathy about his career and the
scientific difficulties he and his laboratory encountered in
their attempts to achieve replication of hepatitis C virus in
cells in culture.


Hosts: Vincent Racaniello and Kathy Spindler


Guest: Charlie Rice


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2020 Nobel Prize (Nobel Prizes)

Hepatitis C human challenge study (Lancet Gastro
Hepatol)

Rat hepacivirus mouse model for hepatitis C
(Hepatol)

Replication of hepatitis C virus in cells in culture
(Science)

Lessons from domestication of HCV (Curr Opin Virol)



Intro music is by Ronald Jenkees


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Content in this podcast should not be construed as medical
advice.