Supplements, Nutrients, and Psychedelics For Sleep, Focus, and Connection with Dr. Scott Sherr

Dr. Scott Sherr has been a frequent guest and audience favorite
with his information-dense guest appearances on The SuperAge
Show. This week we speak about new information on some of the
brain chemical influences on depression, sleep, and anxiety-
specifically the overlooked neurotransmitter GABA. We review the
symptoms of GABA dysregulation and the methods for correcting it.
Dr Sherr is a clinician, meaning he sees patients and comes at
the issues from a more nuanced point of view than pure
researchers sometimes do. In the middle of the episode, Dr Scott
brings up a surprisingly simple zero risk trick to increase sleep
effectiveness. Toward the end of the conversation, David asks
about how to increase concentration and focus, and we get into
the practical usage of nicotine, methyl blue, and low-dose
psychedelics.

Additionally, don’t forget to check out the all-new SuperAge
Quiz!



Thank you to our sponsors: 


SRW Labs – Science Research Wellness — improve your
cellular health. Listeners receive 20% off all products with code
AGEIST20 at SRW.co. 


InsideTracker — the dashboard to your Inner Health.
Listeners get 20% off on all products at
InsideTracker.com/AGEIST.


Ned Mellö Magnesium — essential supplement to improve
sleep, reduce stress, increase energy, and more. Use code
“AGEIST” for 15% off at helloned.com/AGEIST





Key Moments


“So when I do analysis with patients, I'm usually looking at a
gamut of labs and what I found over the last several years is
that GABA is a big problem, and it's not GABA itself that you're
typically looking at, but you're actually looking at some of the
amino acids and some of the cofactors that are typically
deficient in these kinds of patients that are having symptoms
like that are very much correlated with GABA deficiency, and some
of those are symptoms that all of us have gone through in our
life. From a mental health perspective, we know GABA deficiency
is associated with anxiety, with fear, with depression, with
short temper, with phobias, with impulsiveness, with
disorganization, and addiction.”





“The problem with GABA as a supplement is that it's a very big
molecule and it doesn't cross the blood brain barrier very easily
at all. There are only a couple of different ways to get GABA
through. One of them is using something called nicotinoyl GABA or
vitamin B3 attached to a GABA”





“Cava is a GABA agonist so it helps increase the amount of GABA
that binds. It doesn't bind to that GABA site itself, it binds to
a separate site a little further away, but it helps with
increasing the amount of GABA that's going to bind and you're
going to have that feeling of feeling like you've had a couple
beers, kind of thing. But the nice thing about cava is it doesn't
bind with the same affinity and it also binds to other receptors
that help increase wakefulness.”



“The first part of this conversation is that nicotine is a
fantastic cognitive enhancer. It's very short acting. It's about
one to two hours and if you don't smoke it or vape it, keep it
very low, and dose less than four milligrams a day. The chance of
addiction is minutely small, minuscule. So it's very, very
powerful and very quick, and so for people that are looking to
feel more of a cognitive edge. They can actually just have some
nicotine on its own and it will do that.“



Connect with Dr. Sherr


Instagram


HBOT


Say hi to the AGEIST team!