Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping

In this episode, I explain how nicotine impacts the brain and body,
including its potent ability to enhance attention, focus, and
alertness, increase blood pressure and metabolism and reduce
appetite. I discuss nicotine’s ability to increase the action of
neurochemicals, including dopamine, norepinephrine, and
acetylcholine and activate sympathetic (alertness-promoting) neural
circuits. I also discuss common nicotine delivery methods, such as
cigarettes, vaping, dip, and snuff, and how they each create their
own unique experience and how they, but not nicotine itself, cause
cancer and other adverse health effects. I also explain
science-based tools to permanently quit smoking cigarettes or
vaping, including peer-reviewed clinical hypnosis tools,
antidepressants, and alternative nicotine replacement (patches,
lozenges, gums etc.). As nicotine is one of the most widely used
substances with billions of users — most of whom report wanting to
quit — this episode ought to be of interest to former/current
nicotine users, those who want to quit smoking or vaping and/or
those interested in learning the biology behind how nicotine
impacts the brain and body. For the full show notes, visit
hubermanlab.com. Thank you to our sponsors AG1:
https://athleticgreens.com/huberman LMNT:
https://drinklmnt.com/hubermanlab Waking Up:
https://wakingup.com/huberman Momentous:
https://livemomentous.com/huberman Timestamps (00:00:00) Nicotine
(00:03:41) Tool: Brief Daily Meditation & Focus (00:05:59) The
Arrow Model of Focus, Alpha GPC & Garlic Supplements (00:10:05)
Sponsor: LMNT (00:14:35) Nicotine Effects vs. Methods of Delivery,
Acetylcholine (00:19:55) Where is Nicotine Found? Nicotinic
Acetylcholine Receptors (00:25:12) Nicotine & Effects on the
Brain: Appetite, Dopamine & GABA (00:29:37) Sponsor: AG1
(00:32:11) Nicotine, Acetylcholine & Attentional “Spotlighting”
(00:37:29) Nicotine, Norepinephrine & Alertness/Energy
(00:41:10) Nicotine & Effects on Appetite & Metabolism
(00:46:47) Nicotine & Effects on Body: Sympathetic Tone
(00:51:29) Nicotine & Cognitive Work vs. Physical Performance
(00:55:08) Nicotine Delivery Methods & Side Effects, Young
People & Dependency (00:58:35) Smoking, Vaping, Dipping &
Snuffing: Carcinogens & Endothelial Cells (01:02:34) Smoking,
Vaping, Dipping & Snuffing: Negative Impacts on Lifespan &
Health (01:09:23) How to Quit Smoking, Nicotine Cravings &
Withdrawal (01:13:56) Vaping & Nicotine, Rates of Effect Onset,
Dopamine, Addiction & Depression (01:25:06) Tool: Quitting
Smoking & Clinical Hypnosis, Reveri (01:30:16) Bupropion
(Wellbutrin) & Quitting Smoking (01:36:24) Tool: A Nicotine
Replacement Schedule to Quit Smoking, Nicotine Patch/Gum (01:41:52)
Tool: Biological Homeostasis & Nicotine Withdrawal, The “First
Week” Strategy (01:51:39) Zero-Cost Support, YouTube Feedback,
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