Diet & Nutrition for Mental Health | Dr. Chris Palmer

My guest this episode is Chris Palmer, M.D., a board-certified
psychiatrist and assistant professor of psychiatry at Harvard
Medical School. He explains the important connection between
nutrition, metabolism and mental health and his pioneering work
using the ketogenic diet to successfully treat patients with
various mental illnesses, including depression and schizophrenia.
Dr. Palmer explains how the ketogenic diet is an evidenced-based
treatment for epilepsy, mimics the fasted state and can offset the
cognitive decline in Alzheimer’s. He describes the key roles of
mitochondria in mental health, how certain conditions likely arise
from mitochondrial dysfunction, and how low-carbohydrate diets
increase mitochondrial turnover to improve mental health. He also
explains how low-carbohydrate diets positively impact the gut
microbiome and weight loss, important risk factors for
mitochondrial health such as marijuana and alcohol, and the best
way to increase circulating ketones depending on individual needs.
We also cover how a ketogenic diet impacts mood, sleep, and
fertility. Dr. Palmer’s work stands as a revolutionary approach to
mental health and disease that, given the prevalence of mental
health challenges, should be of interest to people of all
backgrounds and ages. For the full show notes, visit
hubermanlab.com. Thank you to our sponsors AG1:
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https://drinklmnt.com/hubermanlab Waking Up:
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https://livemomentous.com/huberman Timestamps (00:00:00) Dr. Chris
Palmer, Mental Health & Metabolic Disorders (00:03:42) Sponsor:
LMNT (00:07:18) Nutrition & Mental Health (00:20:43) Low-Carb
Diets & Anti-Depression, Fasting, Ketosis (00:27:52)
Schizophrenia, Depression & Ketogenic Diet (00:33:58) Sponsor:
AG1 (00:35:38) Psychiatric Mediations, Diet Adherence (00:42:35)
Highly Processed Foods, Ketones & Mental Health Benefits
(00:46:51) Ketogenic Diet & Epilepsy Treatment (00:56:10)
Ketogenic Diet & Mitochondria Health (00:57:05) Nutrition &
Benefits for Neurologic/Psychiatric Disorders (01:05:44)
Mitochondrial Function & Mental Health (01:15:12) InsideTracker
(01:16:23) Mitophagy, Mitochondrial Dysfunction, Aging & Diet
(01:25:09) Neurons, Mitochondria & Blood Glucose (01:31:54)
Obesity, Ketogenic Diet & Mitochondria (01:40:00) Mitochondrial
Function: Inheritance, Risk Factors, Marijuana  (01:46:34)
Alcohol & Ketogenic Diet (01:55:21) Brain Imaging, Alzheimer’s
Disease & Ketones (02:01:05) Exogenous (Liquid) Ketones vs.
Ketogenic Diet (02:06:27) Neuronal Damage, Ketones &
Glucose  (02:10:16) Alzheimer’s Disease, Age-Related Cognitive
Decline & Ketogenic Diet (02:23:45) Ketogenic Diet & Weight
Loss (02:35:47) Ketogenic Diet & Fasting, Hypomania, Sleep
(02:46:37) Low Carbohydrate Diets, Menstrual Cycles, Fertility
(02:52:23) Obesity Epidemic, Semaglutide & GLP-1
Medications  (03:01:01) Zero-Cost Support, YouTube Feedback,
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