How Cannabis Impacts Health & the Potential Risks | Dr. Matthew Hill

In this episode, my guest is Dr. Matthew Hill, Ph.D., a professor
of cell biology and anatomy at the Hotchkiss Brain Institute at the
University of Calgary and an expert on the biology of cannabis. We
discuss how cannabis affects the brain to produce its psychoactive
effects (feeling “high”), including altered time perception, focus,
memory, appetite, and stress. We discuss how THC vs. cannabidiol
(CBD) affects the brain, the effects of different routes of
cannabis administration (e.g., smoking, vaping, edibles),
high-potency THC, and whether cannabis is addictive. We discuss if
there is a link between cannabis use and the development of
psychosis, anxiety, bipolar depression, or schizophrenia.  We
discuss whether CBD has clinical benefits in regulating stress,
promoting sleep, and treating certain diseases. We also discuss if
there are real and consistent differences in the biological effects
of different cannabis strains, if cannabis impacts hormones, and
the uses of cannabis for the management of pain, stress,
Post-traumatic stress disorder (PTSD), anxiety, and nausea.
Listeners of this episode will get an up-to-date understanding of
what is currently known about how cannabis affects the brain and
body, including both its potential benefits and risks. Access the
full show notes for this episode at hubermanlab.com. Thank you to
our sponsors AG1: https://drinkag1.com/huberman Eight Sleep:
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https://drinklmnt.com/huberman BetterHelp:
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https://insidetracker.com/huberman Timestamps 00:00:00 Dr. Matthew
Hill 00:00:00 Sponsors: Eight Sleep, LMNT & BetterHelp 00:07:16
Cannabis, THC, Cannabidiol (CBD), Terpenes 00:12:08 Psychoactive
Effects, Cannabis “High”; Time Perception 00:16:55 Cannabis &
Brain, CB1 Receptor, Endocannabinoids 00:26:19 Endocannabinoids
Types: Anandamide, 2-AG 00:33:46 “Munchies”, Cannabis &
Appetite 00:42:17 Sponsor: AG1 00:44:06 THC & Anandamide,
Pharmacology 00:52:37 THC & CB1 Receptors, Intoxication &
Appetite 00:58:57 Cannabis & Focus, Memory 01:04:09 Routes of
Administration, Concentration, Cannabis Research 01:15:12
Self-Regulation, Inhalation & THC, Tolerance; THC Concentrates
01:22:25 Sponsor: InsideTracker 01:23:36 Addiction & Cannabis,
Cannabis Use Disorder 01:31:30 Cannabis Legalization & Use,
Edibles & ER Visits 01:36:48 Oral Consumption, Edibles, Dosing
& Time Course 01:41:12 Drug Testing & Cannabis, Exercise
01:46:04 Cannabis & Hormones, Gynecomastia, Sperm Quality
01:54:37 Cannabis & Pregnancy; Selling Recreational Cannabis
02:04:07 Vaping 02:07:05 Psychosis, Anxiety & Cannabis 02:17:17
Cannabis, Psychosis, Schizophrenia & Genetics 02:30:45 Cannabis
Use & Schizophrenia, Manic Bipolar, THC Potency, Nicotine
02:40:37 Schizophrenia, Cannabis Legalization 02:45:06 Cannabis
Strains, Indica, Sativa, Subjective Effects & Expectancy Bias
02:57:00 CBD, Pediatric Epilepsy, Adenosine 03:07:22 Entourage
Effect; Placebo Effect, CBD & Doses 03:19:12 Cannabis Health
Risks, Cardiovascular Risk, Schizophrenia  03:27:08 Cyclic
Vomiting Syndrome & Hot Shower 03:31:30 Cannabis Benefits:
Pain, Stress, Anxiety, Post-Traumatic Stress Disorder (PTSD)
03:40:18 Cannabis & Anxiety, Anandamide & Stress Response
03:45:55 Scientific Discussion, Clarification & Advancement
03:49:47 Zero-Cost Support, YouTube, Spotify & Apple Follow
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