How Silent Inflammation Accelerates Aging with Dr. David Furman

This episode is brought to you by Rupa Health, BiOptimizers, and
InsideTracker. If you’re interested in health, you’ve heard the
term inflammation quite a bit. But did you know there are different
kinds of inflammation? Some of them are more alarming than others.
Acute inflammation happens when you cut your finger and it gets red
and a little swollen. This is helpful inflammation and usually
resolves in about a week. But the inflammation that naturally
happens as we age, called sterile-inflammation, sets us up for less
resiliency against things like autoimmunity, cancer, and other
forms of chronic disease.  Today, I’m excited to dive deep
into the topic of inflammation and its role in aging with Dr. David
Furman. Dr. David Furman is Associate Professor and Director of the
Bioinformatics Core at the Buck Institute for Research on Aging, as
well as the Director of the Stanford 1000 Immunomes Project. He
obtained his doctoral degree in immunology from the School of
Medicine, University of Buenos Aires, Argentina, for his work on
cancer immune-surveillance. During his postdoctoral training at the
Stanford School of Medicine, Dr. Furman focused on the application
of advanced analytics to study the aging of the immune system in
humans. This episode is brought to you by Rupa Health,
BiOptimizers, and InsideTracker. Rupa Health is a place where
Functional Medicine practitioners can access more than 2,000
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InsideTracker is a personalized health and wellness platform like
no other. Right now they’re offering my community 20% off at
insidetracker.com/drhyman. Here are more details from our interview
(audio version / Apple Subscriber version): The origins of Dr.
Furman’s unique thinking about the immune system and aging (7:21 /
3:58)  Types of inflammation (11:13 / 8:02)  How systemic
chronic inflammation drives all of the hallmarks of aging (13:32 /
10:30)  Causes of inflammation (18:24 / 13:46)  The
immunome and the 1000 Immunomes Project (26:31 / 21:14)  How
inflammatory age can be used to predict disease (33:13 /
27:12)  Predicting frailty in individuals years before they
become frail (35:54 / 30:37)  Newly discovered biomarkers that
can be used for early detection of age-related disease (38:54 /
32:02)  How the iAge test will be used in the future (47:58 /
43:42)  Learnings from centenarians (59:24 / 54:12) 
Learn more about the 1000 Immunomes Project.