Illuminating the Dark Genome – New Insights into the Genetic Basis of Disease

More than 20 years after the Human Genome Project, enabled by new
sequencing technologies, researchers are making progress in
exploring the vast non-coding space that constitutes 98% of our
genomes. This non-coding, or "dark," DNA harbors elements with
important regulatory functions in health and disease. But
pinpointing disease-relevant DNA elements within this massive DNA
space can be like searching for a needle in a haystack. This
difficult search can be eased by artificial intelligence (AI)-based
tools, which predict the context-dependent relevance of certain DNA
elements and highlight their role in different diseases, from
cancer to rare neurodegenerative disorders. For Episode 33 of the
BioRevolution podcast, Andreas Horchler and Louise von Stechow are
joined by CTO and co-founder of Berlin-based biotech LUCID
Genomics, Dr. Hossein Moeinzadeh, to discuss the exciting field of
non-coding DNA and how LUCID’s AI algorithm can help make sense of
non-coding DNA — and how this could improve diagnoses of rare
diseases and beyond. Learn more about LUCID genomics AI tool here:
https://www.lucid-genomics.com/technology Find Dr. Hossein
Moeinzadeh here: https://www.linkedin.com/in/mhossein-moeinzadeh/
Disclaimer: Louise von Stechow & Andreas Horchler and their
guests express their personal opinions, which are founded on
research on the respective topics, but do not claim to give
medical, investment or even life advice in the podcast. Learn more
about the future of biotech in our podcasts and keynotes. Contact
us here: scientific communication: https://science-tales.com/
Podcasts: https://www.podcon.de/ Keynotes:
https://www.zukunftsinstitut.de/louise-von-stechow Image: via
Unsplash.