Water: Action at a Distance, Light Speed Computation, Distributed Memory - Dr. Michael Hughes, #302

Today we're back, for a third podcast, with long time friend of
the pod, Dr. Michael Hughes - a biochemist at St. Jude's Research
Hospital in Memphis, TN. We plunge into the secret story of
water, revealing its role as more than a silent spectator in the
dance of cellular processes. Like a conductor in an unseen
ballet, water’s dynamic and nuanced structures orchestrate
communication across cells, acting as a transient computationally
competent actuator. Michael reveals how much of this story has
been buried for years under blanket abstractions like "pH" and
electrochemistry. We see the emergence of a new paradigm in
cellular computation, as we uncover how water may not just be the
medium of life — at times it’s perhaps every bit as alive as we
are. PATREON: get episodes early + join our weekly Patron Chat
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through this link: https://amzn.to/3YyoT98 References from
Michael: Na+ vs K+ water dynamics:
https://pubs.rsc.org/en/content/articlelanding/2017/sc/c6sc03320b
; https://pubmed.ncbi.nlm.nih.gov/23713450/ Ion pairing &
Collins’ Law of water affinity:
https://doi.org/10.1017/S0033583519000106 Kosmotropes/Chaotropes
ion pairing in biochemistry review:
https://pmc.ncbi.nlm.nih.gov/articles/PMC4693242/ Osmotic
pressure influences stem cell differentiation:
https://www.pnas.org/doi/10.1073/pnas.1705179114 Hydration as a
primary factor in carcinogenesis:
https://pubmed.ncbi.nlm.nih.gov/16271440/ Distinguishing
electrical properties of cancer cells:
https://www.sciencedirect.com/science/article/abs/pii/S157106452200063X
Heart is not a pump:
https://rsarchive.org/OtherAuthors/MarinelliRalph/marinelli1.html
Laszlo Boros water metabolism:
https://www.youtube.com/watch?v=0g8OLChXta8 (00:00) Go!
(00:09:24) Revisiting Water's Unknowns in Biology (00:22:44)
Osmotic Pressure as Dark Matter (00:30:38) Water Molecule
Interactions (00:35:37) Collective Motion and Electricity
(00:44:35) Memory of Water, for Real (00:48:09) Disappearing
Polymorphs and Chemical Synthesis (00:51:05) Understanding Water
Freezing and Supercooling (00:59:05) pH, Charge, and Biological
Systems (01:08:38) Tetrahedral Ordering in Water Structures
(01:17:01) Energy Transfer and Cellular Connectivity (01:30:00)
Back to pH (01:39:10) Cosmotropes and Chaotropes (01:49:57) Ion
Dynamics in Cells (01:57:15) Unconventional Views on
Consciousness and Physiology #water , #structuredwater ,
#paradigmshift , #Biochemistry, #ScienceExplained,
#Electrochemistry, #NewParadigm, #WaterInBiology,
#CellularCommunication, #PhaseTransitions, #Biophysics,
#MolecularScience, #SciencePodcast, #ScientificBreakthrough,
#WaterStructure, #EmergingScience, #CellBiology,
#BiochemicalMysteries, #pHExplained, #scientificinnovation
#sciencepodcast, #longformpodcast Check our short-films channel,
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https://bit.ly/3v3kz2S PODCAST INFO: Anastasia completed her PhD
studying bioelectricity at Columbia University. When not talking
to brilliant people or making movies, she spends her time
painting, reading, and guiding backcountry excursions. Shilo also
did his PhD at Columbia studying the elastic properties of
molecular water. When he's not in the film studio, he's exploring
sound in music. They are both freelance professors at various
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