178. Isabelle Kenyon, Founder & CEO of Calibrate

Today, I’m joined by Isabelle Kenyon, founder & CEO of
Calibrate, a weight loss platform complementing lifestyle
coaching with prescription medication.


Calibrate helps people achieve sustainable weight loss and
metabolic health through personalized clinical and lifestyle
interventions. Founded in 2020, the company’s evidence-based
programming, expert coaching, and FDA-approved GLP-1 medication
has positioned it as a leader in taking on the obesity epidemic.


In this episode, we discuss the company’s metabolic reset
program, explore the rapid growth of prescription weight loss
drugs, and cover the ongoing debate over how best to treat
obesity.


In this episode, you’ll learn:


• Why Calibrate believes weight loss is about biology, not
willpower
• The company’s methodology for prescribing GLP-1
medication
• Isabelle and Joe’s perspectives on healthy weight loss and
prescription medication


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Chapters:
(00:00) Introduction
(01:15) About Calibrate
(02:39) Enterprise vs. DTC business model
(03:39) GLP-1 potential TAM
(05:10) What differentiates Calibrate?
(08:29) Finding the ideal long-term care model for patients
(12:59) Is obesity about willpower or biology?
(19:01) Metabolic health and food 
(23:07) GLP-1’s that are covered by insurance
(26:20) If the product works, the business works
(29:35) Scaling Calibrate
(30:54) Systemic obesogenic environment
(35:13) Future roadmap
(37:44) Conclusion