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  3. Medizin - Open Access LMU - Teil 17/22 Podcast
  4. Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome
Objective: The aim of the study was a prospective assessment of
patient-reported side effects in an open-label study after
intradetrusor botulinum toxin injections for idiopathic overactive
bladder (OAB). Patients and Methods: Botulinum toxin A injection
was performed in 56 patients with idiopathic OAB. Patients were
followed up for 6 months concerning side effects and patients'
satisfaction. Results: Different types of side effects were
assessed such as dry mouth (19.6%), arm weakness (8.9%), eyelid
weakness (8.9%), leg weakness (7.1%), torso weakness (5.4%),
impaired vision (5.4%) and dysphagia (5.4%). In all cases, symptoms
were mild and transient. Urological complications such as gross
hematuria (17.9%), acute urinary retention (8.9%) and acute urinary
tract infection (7.1%) were noticed. In all cases, acute urinary
retention was transient and treated with temporary intermittent
self-catheterization. There was no statistically significant
correlation between dosage and observed side effects. Patients'
satisfaction rate was high (71.4%). Conclusion: Intradetrusor
injection of botulinum toxin was associated with a high rate of
neurourological side effects. In general, side effects were
transient, mild and did not require special treatment. Copyright
(C) 2010 S. Karger AG, Basel

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„Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome“

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