CTCF binding, nucleosome positioning and 3D chromatin organization with Dr Christopher Clarkson

In today's episode, we are excited to be talking to Dr
Christopher Clarkson, currently based at UCL, where he has just
started a post-doctoral research position.


In 2020, Dr. Clarkson completed his PhD at the University of
Essex where he investigated changes of nucleosome positioning and
3D chromatin organization! In today's episode, we discuss how
CTCF binding strength correlates with nucleosome repeat length
and what the implications are of this on gene regulation. We
further discuss how regions in the genome where CTCF is able to
bind are extremely important for cellular differentiation and
boundary formation within the genome.


Email: c.clarkson@ucl.ac.uk


Chris' Nucleic Acid Research article: CTCF-dependent chromatin
boundaries formed by asymmetric nucleosome arrays with decreased
linker length


Twitter: find Chris on twitter here.





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