New methods for healing bone fractures

New methods for healing bone fractures

In the future bone fractures could be glued with calcium phosphate nano particles and reduce surgery and const.
35 Minuten
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Talking to scientist about their innovations in chemistry
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Düsseldorf

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vor 1 Jahr
Thanks for considering to support the show on
buymeacoffee.com/innovateandreact ️ The development of bone
adhesives represents an exciting advancement at the intersection of
material science and medicine. Traditional fracture treatments rely
on metal implants such as screws and plates, which, while
effective, come with drawbacks like high costs, the need for
secondary surgeries, and potential long-term complications. Bone
adhesives offer a promising alternative by providing a
biodegradable solution that bonds bone fragments together while
gradually being replaced by natural bone tissue. This could
significantly reduce the overall cost and invasiveness of fracture
treatments, improving patient recovery and outcomes. Despite this
potential, significant challenges remain. A major hurdle is finding
the right balance between adhesive strength and biocompatibility.
Many strong adhesives, such as cyanoacrylates, are bioinert and do
not integrate with bone, while biodegradable materials often lack
the necessary mechanical stability. Research has explored various
approaches, including modifying calcium phosphate nanoparticles
with catechol groups inspired by mussels or using peptide-based
bonding agents. However, these methods have faced issues such as
instability, insufficient fracture stabilization, or prohibitively
high costs. Future advancements may come from further optimizing
hydrogel-based adhesives and developing better cross-linking
techniques to enhance durability while maintaining
biocompatibility. Looking ahead, bone adhesives could first see
practical applications in dentistry, where they can be used for
procedures that require strong, biocompatible bonding without the
complexity of bone remodeling. If successful, these adhesives could
eventually replace traditional metal implants in orthopedic
surgery, particularly for fractures in non-load-bearing bones.
However, further research and clinical trials are needed to refine
these materials and confirm their long-term effectiveness. With
continued progress, bone adhesives have the potential to
revolutionize fracture treatment, making it more efficient,
cost-effective, and patient-friendly.

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