Sandeep K. Gupta, MD - Updates in Eosinophilic Esophagitis: Exploring Underlying Mechanisms and Integrating Novel Targeted Therapy to Improve Patient Care

Go online to PeerView.com/MKN860 to view the activity, download
slides and practice aids, and complete the post-test to earn
credit. Eosinophilic esophagitis (EoE) is an increasingly
prevalent, chronic, T2 inflammatory disease triggered by food
and/or environmental allergens. Due to underlying tissue
inflammation, patients suffer diminished quality of life due to
symptoms such as weight loss, difficulty swallowing, and heartburn.
Patients can experience these symptoms for a long time before
receiving a proper diagnosis. Once diagnosed, treatment options
have historically been limited. Fortunately, therapies that treat
other type 2 disorders are in development or are approved to treat
EoE. At a recent live event, experts used patient cases to discuss
the diagnosis, underlying causes, and the newest treatments for
EoE, including biologic therapies. Watch this on-demand version
now! Upon completion of this activity, participants should be
better able to: Distinguish signs and symptoms of eosinophilic
esophagitis (EoE) among children and adults to enable an earlier
diagnosis and minimize complications due to uncontrolled disease;
Recognize underlying mechanisms of EoE, including the role of key
cytokines such as interleukins -4, -13, and -5 as drivers of type 2
inflammation and how this relates to emerging treatment; and Apply
the latest expert recommendations and clinical evidence to the
treatment of patients with EoE, particularly as novel and emerging
agents become available.