#139 - Meet The Greatest Ibogaine Psychedelic Scientist You’ve Never Heard Of

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Dalibor Sames is the chemist who reverse-engineered ibogaine into
a version that appears to erase heroin addiction in a single
dose, without the cardiac risk that can kill people on the
original drug. He also took his own medicine — and says he
watched the molecule's exact 3D structure rotate in front of him
for 36 hours straight.Expect to learn why ibogaine breaks every
rule of classical pharmacology, what "matrix pharmacology" means
and why it's heresy to a one-drug-one-target industry, how
editing a single atom deletes ibogaine's fatal heart risk, why a
common antidepressant turned out to be a secret opioid for thirty
years, what it's like to watch a molecule's structure appear
during a 36-hour flood dose, why ibogaine seems to erase interest
in alcohol overnight, whether the "DMT block" phenomenon
researchers describe is real, and much more…


Timestamps0:00:00


Trailer0:02:39


Meet the Chemist Who Fell for a Molecule's Shape


0:04:13 The Dogma That the Adult Brain Can't Heal0:09:00 Why
Synapses Might Explain Every Brain Disorder0:10:28
Reverse-Engineering Nature's Own Drugs


0:16:44 The Paper That Changed Everything About Addiction


0:20:01 Why Ibogaine Breaks Every Rule of Pharmacology


0:33:08 The Weakest Drug That Works the Strongest


0:38:21 The Traffic Jam That Explains Matrix Pharmacology


0:44:18 A Human Genome Project — For One Molecule


0:47:48 Deciding to Take Ibogaine Himself


0:50:02 Inside a 36-Hour Flood Dose


0:54:38 The Chapter Called "Treatment"


0:56:26 Ibogaine Shows Him the Future of Design


1:00:01 Seeing Ibogaine's 3D Molecular Structure


1:03:14 High-Fiving a Molecule1:06:47 "This Is a Computational
Technology"


1:16:36 The Simulation So Real It Panicked Him


1:24:26 Did He Earn This Experience?


1:30:56 Six Months Later — What Actually Changed


1:36:01 Did This Change His View of Consciousness?......


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GS Episodes Mentioned


Andrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT
Entity Encounters, Attractor States and Consciousness:
https://www.youtube.com/watch?v=USgWrxEFWDA


David Luke — Meet the Professor of Paranormal Consciousness - DMT
Entities, Telepathy Tapes & OBE's:
https://www.youtube.com/watch?v=qLKD1gt1X5oGuest


LinksColumbia Chemistry faculty page:
https://www.chem.columbia.edu/content/dalibor-sames


Sames Lab: https://www.samesgroup.org/professor-dalibor-sames


Gilgamesh Pharmaceuticals:
https://www.gilgameshpharmaceutical.com/


Oxa-Iboga paper (Nature Communications, 2024):
https://doi.org/10.1038/s41467-024-51856-y


Beond Ibogaine Clinic (where he took ibogaine):
https://beondibogaine.com