#96 - Interview with John Klepper - Serial Entrepreneur, Board Member, Strategist, Innovator, Speaker and founder
How AI is transforming delirium prevention, and redefining patient
care
34 Minuten
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️ CapricornConnect Podcast – New Episode Delirium is one of the
most devastating, and overlooked, conditions in healthcare.
Affecting nearly 1 in 4 hospital patients over the age of 60, it
can lead to hallucinations, cognitive decline, longer hospital
stays, and permanent loss of independence. Yet in many cases, it is
preventable. In this episode of the CapricornConnect Podcast, we
speak with John Klepper, serial entrepreneur and Founder & CEO
of PIPRA, about how AI is transforming delirium prevention in
hospitals worldwide. John’s journey into healthcare innovation is
deeply personal. After working in Alzheimer’s prevention, his own
mother experienced delirium during a hospital stay—an event she
later described as the most terrifying experience of her life. That
moment inspired the creation of PIPRA’s non-pharmacological,
AI-based technology, which predicts delirium risk before onset and
enables proactive care pathways. Proven hospital results include: -
Switzerland: 29% reduction in delirium cases - Spain (Madrid): 43%
reduction - Germany (Munich): 72% reduction Beyond patient
outcomes, delirium carries enormous economic costs—exceeding those
of diabetes—driven by longer stays, readmissions, and
complications. We also discuss: - John’s unconventional path from
the film industry (The Matrix) to health tech - Why culture and
intuition matter more than perfect CVs when building teams - The
emotional realities of entrepreneurship - Why empathy is a critical
leadership skill in the age of AI This episode explores how AI,
when built with empathy and evidence, can save lives and reshape
healthcare systems.
most devastating, and overlooked, conditions in healthcare.
Affecting nearly 1 in 4 hospital patients over the age of 60, it
can lead to hallucinations, cognitive decline, longer hospital
stays, and permanent loss of independence. Yet in many cases, it is
preventable. In this episode of the CapricornConnect Podcast, we
speak with John Klepper, serial entrepreneur and Founder & CEO
of PIPRA, about how AI is transforming delirium prevention in
hospitals worldwide. John’s journey into healthcare innovation is
deeply personal. After working in Alzheimer’s prevention, his own
mother experienced delirium during a hospital stay—an event she
later described as the most terrifying experience of her life. That
moment inspired the creation of PIPRA’s non-pharmacological,
AI-based technology, which predicts delirium risk before onset and
enables proactive care pathways. Proven hospital results include: -
Switzerland: 29% reduction in delirium cases - Spain (Madrid): 43%
reduction - Germany (Munich): 72% reduction Beyond patient
outcomes, delirium carries enormous economic costs—exceeding those
of diabetes—driven by longer stays, readmissions, and
complications. We also discuss: - John’s unconventional path from
the film industry (The Matrix) to health tech - Why culture and
intuition matter more than perfect CVs when building teams - The
emotional realities of entrepreneurship - Why empathy is a critical
leadership skill in the age of AI This episode explores how AI,
when built with empathy and evidence, can save lives and reshape
healthcare systems.
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