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Fakultät für Chemie und Pharmazie - Digitale Hochschulschriften der LMU - Teil 02/06 Podcast
Offenkettige Monosaccharide als Liganden

Offenkettige Monosaccharide als Liganden

Fakultät für Chemie und Pharmazie - Digitale Hochschulschriften der LMU - Teil 02/06 vor 19 Jahren

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In this thesis novel carbohydrate transition metal complexes are
presented. As transition metals rhenium(V), copper(II) and
palladium(II) are used, and their complexation behaviour towards
carbohydrates is investigated. Various carbohydrates, such as
tartaric acid, xylaric acid, polyols, hydroxyaldehydes,
glyceraldehyde, erythrulose, erythrose, threose and xylose act as
ligands in these coordination compounds. The complexes are
synthesised and characterised by NMR spectroscopy and single
crystal X-ray diffraction. Heteroleptic complexes of copper(II)
with xylaric acid and tartaric acid are synthesised and
characterised. Different ancillary ligands such as bpma and tpa are
used. In these structures the coordination number of copper(II)
varies from 4 to 6, and different geometries depending on the
ancillary ligand are observed. At last the reactivity of
palladium(II) towards highly reducing sugars and aldehydes such as
D-erythrose, D-threose, D-erythrulose, D-glyceraldehyde, glyoxal
and glycolaldehyde is investigated. Complexes of the hydrated
aldehydes can be observed in solution, with the hydrate
coordinating up to two metal centers. For the first time complexes
of monosaccharides in their open chain form can be identified and
characterised in solution. These forms are stabilised and enriched
in solution by palladium(II). The crystal structure of a
palladium(II)-erythrose complex is presented, which is the first
crystal structure of this tetrose as yet.