Intima-Media-Thickness (IMT) bei Patienten mit vertebrobasilären und karotidalen Stenosen/Verschlüssen
Beschreibung
vor 20 Jahren
Introduction: The Intima-Media-Thickness (IMT) of the commom
carotid artery (CCA) is often used as a parameter for generalized
atherosclerotic lesions of the vessel wall. It is possible to
visualize the increase of the IMT in an early degree of
athrosclerosis as a double line pattern in the sonographical
picture (B-mode). The demographic difference of the IMT (e.g.
between men an women) and the effect of the classical
cerebrovascular risk factors on the IMT are sufficiently known. The
difference of the side (right and left carotid artery) and the
localisation in the carortid arteries of the IMT are already
illuminated. It is not known actually, if different types of
atherosclerosis are accompanied by a different IMT. The purpose of
the study was to invesigate the IMT in patients with stenoses or
occlusions in the vertebrobasilar system (VBS) and the carotid
system (CS). Patients and methods: The Intima-Media-Thickness (IMT)
and the diameter (QD) of the common carotid artery (CCA) (as a
parameter of proliferative and dilatative form of atherosclerosis)
were measured on both sides on areas of vessel wall without
stenoses and plaques. We examined of the neck 121 people, including
32 normal healthy counds, 57 patients with stenoses or occlusions
in the CS and 16 patients with macroangiopathy exclusively in the
VBS. Patients of the fourth group (n=16) suffered from both VBS-
and CS-macroangiopathy (CS/VBS) (following doppler- and duplex
sonographical criteria). The classical cerebrovascular risk factors
(age, arterial blood pressure, hypercholesterolemia, diabetes
mellitus, family history, smoking status) were entered in a
questionnaire. Results: In control persons, a IMT of 0,67±0,2 mm
and a CCA-diameter of 5,8±1,2 mm was found. Patients with
CS-macroangiopathy exhibited a significant higher IMT with 0,97±0,2
mm (p
carotid artery (CCA) is often used as a parameter for generalized
atherosclerotic lesions of the vessel wall. It is possible to
visualize the increase of the IMT in an early degree of
athrosclerosis as a double line pattern in the sonographical
picture (B-mode). The demographic difference of the IMT (e.g.
between men an women) and the effect of the classical
cerebrovascular risk factors on the IMT are sufficiently known. The
difference of the side (right and left carotid artery) and the
localisation in the carortid arteries of the IMT are already
illuminated. It is not known actually, if different types of
atherosclerosis are accompanied by a different IMT. The purpose of
the study was to invesigate the IMT in patients with stenoses or
occlusions in the vertebrobasilar system (VBS) and the carotid
system (CS). Patients and methods: The Intima-Media-Thickness (IMT)
and the diameter (QD) of the common carotid artery (CCA) (as a
parameter of proliferative and dilatative form of atherosclerosis)
were measured on both sides on areas of vessel wall without
stenoses and plaques. We examined of the neck 121 people, including
32 normal healthy counds, 57 patients with stenoses or occlusions
in the CS and 16 patients with macroangiopathy exclusively in the
VBS. Patients of the fourth group (n=16) suffered from both VBS-
and CS-macroangiopathy (CS/VBS) (following doppler- and duplex
sonographical criteria). The classical cerebrovascular risk factors
(age, arterial blood pressure, hypercholesterolemia, diabetes
mellitus, family history, smoking status) were entered in a
questionnaire. Results: In control persons, a IMT of 0,67±0,2 mm
and a CCA-diameter of 5,8±1,2 mm was found. Patients with
CS-macroangiopathy exhibited a significant higher IMT with 0,97±0,2
mm (p
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