Medizin - Open Access LMU - Teil 05/22 Archiv

A familiar relation links the densities that result for the intersection of a convex body and straight lines under uniform isotropic randomness with those that result under weighted randomness. An extension of this relation to the intersection of more general domains is utilized to obtain the variance of the n-dimensional measure of the intersection of two bodies under uniform isotropic randomness. The formula for the variance contains the point-pair distance distributions for the two domains — or the closely related geometric reduction factors. The result is applied to derive the variance of the intersection of a Boolean scheme, i.e. a stationary, isotropic Poisson process of domains, with a fixed sampling region.

We compiled and evaluated the world literature on auricular reconstruction, for a total of over 400 publications, more than 200 authors, and over 3,300 reported cases. We found that partial reconstructions were already performed as early as 600 BC; total reconstructions were still considered impracticable in 1830. But since 1891, more than 40 different cartilaginous, osseous, and alloplastic frame materials have been described. Only eight of these were still being applied in the last decade, with autogenous costal cartilage and silicone as the leading substances. Results of the operation can be improved by special surgical manipulations, eg, the "fan-flap" technique. Taking into consideration the complication rate, the number of individual interventions, and the stability of the results, we devised a special point system that makes possible a limited assessment of the different surgical techniques.

Ascitic fluid concentrations of cholesterol, triglycerides and phospholipids, were compared with ascitic fluid total protein in 40 patients with chronic liver disease, 51patients with various neoplasms and 1 patient with cardiac failure. Seven patients withboth chronic liver disease and malignancy were considered separately. The first 54 patients (23 cirrhotic and 31 with malignancy) were used to determine median values and ranges and to define the most suitable cutoff concentrations between both groups. Median values for cholesterol (75 mg per dl), phospholipids (0.79 mmole per liter), triglycerides (75 mg per dl) and protein (3.8 gm per dl)were higher in malignant ascites compared to ascitic fluid concentrations of cholesterol (20 mg per dl), phospholipids (0.33 mmole per liter), triglycerides (51 mg per dl) and protein (1.9 gm per dl) in patients withcirrhosis. The best discrimination values were 48 mg per dl for cholesterol, 0.6 mmole per liter for phospholipids, 65 mg per dl for triglycerides and 2.5 gm per dl for protein. Application of these cutoff points to 38 subsequent patients (17 cirrhotic, 1 with cardiac failure and 20 with malignancy) revealed an efficiency of 86.8% for cholesterol, 86.8% for phospholipids, 68.4% for triglycerides and 79.0% for protein. From the data of all 92 patients, an efficiency of 92.3% forcholesterol, 79.4% for phospholipids, 72.8% for triglycerides and 79.4% for protein was calculated. We conclude that ascitic fluid cholesterol determination offers an excellent, cost-effective discrimination of ascites due to cirrhosis vs. ascites caused by malignancies.