Leslie Kenny was told in her 30s that she had five years to live.
Diagnosed simultaneously with lupus, rheumatoid arthritis, and
Hashimoto’s thyroiditis — and told to give up her dream of having
children — she did what true Betties do: she refused the
prognosis, threw everything she had at it, and got to work. Now
60 years old, Leslie reports a biological age of 21. She is
autoimmune disease-free. And she naturally conceived a child at
43.
Her recovery journey led her to collaborate with University of
Oxford scientists and to discover spermidine — a naturally
occurring, food-derived longevity compound that was hiding in
plain sight. It’s been in our food for millennia, it’s in breast
milk, and it’s in every plant on earth. And it addresses 9 of the
12 hallmarks of ageing identified by science as the root causes
of why we get older.
For 20% off Primeadine, go to:
https://www.oxfordhealthspan.com/DRSTEPHANIE
Episode Overview (timestamps are approximate):
(0:00) Intro/Teaser
(4:00) What Is Spermidine and Why Do We Lose It?
(8:00) Autophagy, Hair, Nails & the Biological
Dashboard
(17:00) The 12 Hallmarks of Ageing, Explained for Real Life
(23:00) mTOR, Muscle Loss, and Why Spermidine Is Different
(27:00) Food Sources, Dosage & Lifestyle Levers
(38:00) Leslie's Story: The Diagnosis, the Prognosis, the
Refusal
(55:00) IVIG, Trauma Therapy & the Surprise Pregnancy at
43
(1:18:00) Femspan, Future Research & Where to Find
Leslie
(1:22:00) The After-Party Thoughts with Dr. Stephani
Resources mentioned in the Episode can be found at:
https://drstephanieestima.com/podcasts/ep464
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P.S. When you're ready, here are two ways Dr. Stephanie can help
you:
Subscribe: The Mini
Pause — My weekly newsletter packed with the most
actionable, evidence-based tools for women 40+ to thrive in
midlife.
Build Muscle: LIFT — My
progressive strength training program designed for women in
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