In this episode, Dr. Lottie covers everything about Johne’s
disease (also known as paratuberculosis) from the MAP pathogen
itself and what clinical signs you may see, to how we can control
infection and what Johne’s means for public health
Find us on TikTok & Instagram: @veterinaryvista
Timeline:
00:00 Intro
00:45 Case
02:36 Aetiology & Pathogenesis
06:26 Clinical Signs
09:18 Diagnosis
14:46 Treatment
15:59 Prevention
18:42 Impact of Johne’s
21:01 Key Points
22:32 Outro
Recommended Reading:
Johne’s Disease in Canada – Parts I and II
Part I is an overview of clinical signs, how the disease
develops, and common di gnostic approaches then part II focuss
on the economic impact of the disease and control methods .
Canadian Veterinary Journal (2006), Vol 47(9), pp 874–882 and
Canadian Veterinary Journal (2006), Vol 47(11), pp 1089–1099.
Mycobacterium avium subsp. paratuberculosis in
Veterinary Medicine A very readable but detailed
explanation of the bacterium itself and how it behaves.
Clinical Microbiology Reviews (2001).
Veterinary Medicine: A Textbook of the Diseases of
Cattle, Horses, Sheep, Pigs and Goats (11th Edition)
Great cattle textbook chapter on paratuberculosis
Constable, Hinchcliff, Done & Grünberg — pp. 552–572
References
Tiwari, A., VanLeeuwen, J.A., McKenna, S.L.B., Keefe, G.P.
& Barkema, H.W. (2006) ‘Johne’s disease in Canada Part I:
Clinical symptoms, pathophysiology, diagnosis, and prevalence in
dairy herds’, Canadian Veterinary Journal, 47(9), pp. 874–882.
McKenna, S.L.B., Keefe, G.P., Tiwari, A., VanLeeuwen, J.A.
& Barkema, H.W. (2006) ‘Johne’s disease in Canada Part II:
Disease impacts, risk factors, and control programs for dairy
producers’, Canadian Veterinary Journal, 47(11), pp. 1089–1099.
Harris, N.B. & Barletta, R.G. (2001) ‘Mycobacterium avium
subsp. paratuberculosis in Veterinary Medicine’, Clinical
Microbiology Reviews, 14(3), pp. 489–512. doi:
10.1128/CMR.14.3.489-512.2001.
Constable, P.D., Hinchcliff, K.W., Done, S.H. & Grünberg,
W. (2017) Veterinary Medicine: A Textbook of the Diseases of
Cattle, Horses, Sheep, Pigs and Goats. 11th ed. Elsevier, pp.
552–572.
Sweeney, R.W., Collins, M.T., Koets, A.P., McGuirk, S.M.
& Roussel, A.J. (2012) ‘Paratuberculosis (Johne’s Disease) in
Cattle and Other Susceptible Species’, Journal of Veterinary
Internal Medicine, 26(6), pp. 1239–1250. doi:
10.1111/j.1939-1676.2012.01019.x.
Rathnaiah, G., Zinniel, D.K., Bannantine, J.P., Stabel, J.R.,
Gröhn, Y.T., Collins, M.T. & Barletta, R.G. (2017)
‘Pathogenesis, Molecular Genetics, and Genomics of Mycobacterium
avium subsp. paratuberculosis’, Frontiers in Veterinary Science,
4, 187. doi: 10.3389/fvets.2017.00187.
Beard, P.M., Daniels, M.J., Henderson, D., Pirie, A., Rudge,
K., Buxton, D., Rhind, S., Greig, A., Hutchings, M.R.,
McKendrick, I., Stevenson, K. & Sharp, J.M. (2001)
‘Paratuberculosis infection of nonruminant wildlife in Scotland’,
Journal of Clinical Microbiology, 39(4), pp. 1517–1521. doi:
10.1128/JCM.39.4.1517-1521.2001.
Whittington, R., Donat, K., Weber, M.F. et al. (2019)
‘Control of paratuberculosis: who, why and how. A review of 48
countries’, BMC Veterinary Research, 15, 198. doi:
10.1186/s12917-019-1943-4.
World Organisation for Animal Health (WOAH) (2024)
Paratuberculosis. Available at:
https://www.woah.org/en/disease/paratuberculosis/ (Accessed: 30th
October 2025).
Fecteau, M.E. (2018) ‘Paratuberculosis in cattle’, Veterinary
Clinics of North America: Food Animal Practice, 34(1), pp.
209–222. doi: 10.1016/j.cvfa.2017.10.011
Current Vet is an educational podcast intended for veterinary
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interest in veterinary medicine.
All content provided in this podcast and its associated materials
is for educational and informational purposes only. It is not
intended as, and must not be considered a substitute for,
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Any clinical cases discussed in this podcast are fictional, and
are designed to reflect typical or likely clinical scenarios for
educational purposes. They do not represent specific real-life
cases, clients, or animals.
While every effort is made to ensure accuracy and alignment with
current evidence at the time of publication, veterinary medicine
is a rapidly evolving field, and recommendations may change over
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