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From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked (EP. 11)

From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked (EP. 11)

From First Principles vor 11 Monaten

0:00

1:54:25

Hosted by Lester Nare and Krishna Choudhary, this one-episode
special brings all three 2025 Nobel Prizes in the sciences into a
single listen: Medicine (immune tolerance and FOXP3), Physics
(macroscopic quantum tunneling in superconducting circuits), and
Chemistry (metal–organic frameworks and “new rooms for
chemistry”).

Summary

Medicine: Regulatory T cells and the FOXP3
gene that prevent autoimmune disease.

Physics: Macroscopic quantum tunneling and
energy quantization in electrical circuits — the bridge to
today’s qubits.

Chemistry: Metal–Organic Frameworks (MOFs) —
modular porous crystals enabling CO₂ capture, water harvesting,
and hydrogen storage.

Show Notes

Nobel Prize Press Release (2025 Medicine)

Nature Genetics (2001) — FOXP3 mutation and IPEX link

Nature Genetics (2001) — FOXP3 Mutation Causes Dysregulation

Nature Genetics (2001) — FOXP3 Gene Cause IPEX Syndrome

Science (2003) — FOXP3 function in regulatory T cells

German Journal of Immunology (1995) — Sakaguchi’s first Treg
paper

Nobel Prize Press Release (2025 Physics)

Physical Review Letters (1980s) — Macroscopic Quantum
Tunneling Experiments (UC Berkeley)

BCS Theory (1972 Nobel) — Bardeen, Cooper & Schrieffer,
University of Illinois

Josephson Effect (1973 Nobel) — Brian D. Josephson

Google Quantum AI Lab — Quantum Supremacy Paper (Nature,
2019)

Nobel Prize Press Release (2025 Chemistry)

Nature (1999) — MOF-5 Discovery (Omar Yaghi et al.)

Science (2003) — Reticular Chemistry Foundations

Journal of the American Chemical Society (1989, 1990) —
Richard Robson’s Early Frameworks

Lawrence Berkeley National Laboratory — ChatMOF and
AI-Assisted Materials Discovery