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Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)

Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)

From First Principles vor 8 Monaten

0:00

1:51:32

Hosted by Lester Nare and Krishna Choudhary, this episode has two
main stories: an astrophysics update on a candidate “dark galaxy”
in the Perseus Cluster (a halo that’s ~99.9% dark matter), and a
major Alzheimer’s mechanism paper tracing how exercise protects the
brain by repairing the blood–brain barrier—with an actionable
drug-like path already emerging. Summary Candidate dark galaxy —
Hubble + Euclid stacking and globular clusters reveal an
ultra-faint halo that could test missing satellites and the
cusp–core problem (and even “fuzzy dark matter”). Exercise
Alzheimer’s mechanism — UCSF links a liver enzyme (GPLD1) to BBB
repair via TNAP regulation, plus an oral TNAP inhibitor (SBI-425)
that mimics the effect in mice. Rundown — Rubin Observatory’s
real-time alert engine, AI-accelerated magnet discovery, a
climate-corrected Easter Island history, and the Boba-Kiki effect
in baby chicks. Support the showDonate: FFPod.com/donateFollow:
@FFPod (X / Instagram / TikTok / Facebook)