Startseite
Podcasts
From First Principles Podcast
Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)

Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)

From First Principles vor 6 Monaten

0:00

1:51:32

Hosted by Lester Nare and Krishna
Choudhary, this episode has two main stories: an
astrophysics update on a candidate “dark galaxy”
in the Perseus Cluster (a halo that’s ~99.9% dark matter), and a
major Alzheimer’s mechanism paper tracing how
exercise protects the brain by repairing the
blood–brain barrier—with an actionable drug-like
path already emerging.

Summary

Candidate dark galaxy — Hubble + Euclid stacking
and globular clusters reveal an ultra-faint halo that could test
missing satellites and the cusp–core problem (and even “fuzzy
dark matter”).

Exercise Alzheimer’s mechanism — UCSF links a
liver enzyme (GPLD1) to BBB repair via TNAP regulation, plus an
oral TNAP inhibitor (SBI-425) that mimics the effect in mice.

Rundown — Rubin Observatory’s real-time alert
engine, AI-accelerated magnet discovery, a climate-corrected
Easter Island history, and the Boba-Kiki effect in baby chicks.

Support the showDonate:
FFPod.com/donateFollow: @FFPod
(X / Instagram / TikTok / Facebook)