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AI Cancer Vaccines, Strange Fish, Ketamine, and Ancient Life (EP. 34)

AI Cancer Vaccines, Strange Fish, Ketamine, and Ancient Life (EP. 34)

From First Principles vor 7 Monaten

0:00

44:58

Hosted by Lester Nare and Krishna Choudhary, this episode is a
fast-moving science rundown covering four remarkable stories from
across AI, genetics, neuroscience, and paleontology. We dig into
the story of a machine learning engineer who used AI tools to help
design a personalized cancer vaccine for his dog, explore how an
all-female fish species has survived far longer than evolutionary
theory would predict, unpack new brain-scan evidence for how
ketamine may rapidly relieve severe depression, and look at new
research suggesting life rebounded shockingly fast after the
asteroid that killed the dinosaurs. Summary AI and personalized
medicine — a striking case study in how AI tools may help
accelerate highly customized treatments, starting with a rescue dog
named Rosie. Evolution gets weird — the Amazon molly fish appears
to challenge the usual assumptions about why asexual reproduction
should fail over long time scales. Why ketamine works so fast — new
PET imaging research points to brain-region-specific changes in
AMPA receptors in treatment-resistant depression. Life after
catastrophe — microscopic plankton may have evolved into new
species within just a few thousand years after the Chicxulub
impact. Support the showDonate: FFPod.com/donateFollow: @FFPod on X
/ Instagram / TikTok / Facebook Show Notes AI-designed dog cancer
vaccine story
https://finance.yahoo.com/news/mans-dog-riddled-tumors-dying-210500037.html?guccounter=1
Amazon molly / gene conversion paper
https://www.nature.com/articles/s41586-026-10180-9 Ketamine / AMPA
receptor PET imaging paper
https://www.nature.com/articles/s41380-026-03510-w Post-asteroid
plankton recovery paper
https://www.yokohama-cu.ac.jp/english/news/20260306takahashi.html