013 Shawn Wells – On Mitochondrial Health, Supplements, & Tribe

00:57 – Introducing today’s guest, Shawn Wells


05:53 – Shawn breaks down the role of mitochondria its impact on
energy


07:14 – Insufficient Cellular Energy (ICE) states


09:38 – Glycation, explained


12:17 – Signs of accelerated glycation


14:10 – The benefits of the supplement, Berberine


16:22 – The value of context


17:53 – The importance of checking and modulating your blood
sugar


20:23 – How Barberry works


22:09 – How chronic low-grade inflammation can affect our
mitochondria


25:06 – Dr. Stephanie and Shawn discuss why it’s not ideal to
rely on caffeine and other energy boosters that have negative
side effects


28:39 – Dr. Stephanie explains oxidative phosphorylation


29:25 – How keto works


30:49 – Key differences between ketogenic diets and Standard
American Diet


39:41 – Digestive resistant starches


45:39 – Benefits of being metabolically flexible


51:22 – Shawn’s favorite foundational supplements


55:11 – Dr. Stephanie and Shawn talk about the supplement NAD


59:02 – The power of mitochondrial pathways


1:02:21 – The value of recovery


1:03:44 – Happiness


1:06:50 – Sleep deprivation and social jetlag


1:09:19 – Community and sex


1:11:47 – Shawn answers a series of rapid-fire questions


1:18:21 – Where listeners can follow Shawn


1:18:59 – Dr. Stephanie thanks Shawn for joining the show


1:19:23 – Where listeners can follow Dr. Stephanie and subscribe
to her newsletter


TWEETABLE QUOTES


“What happens though, that’s so important that we’re finding out,
why I say, ‘mito is the new keto,’ is that we are often in
insufficient cellular energy states, which is an acronym called
ICE. And, there’s something else that’s in neurological diseases,
it’s a very similar idea called brain energy gap.” (07:14)


“It’s [Berberine] been shown in studies to be as effective, if
not more effective, than Metformin, which is known as an
incredible glucose disposal agent.” (14:47)


“One of the ways that keto works is that you’re not creating as
much oxidation and you are using an alternate fuel source –
ketones – and you are insulin-resistant, and you are in this
insufficient cellular energy state, and you don’t have enough
glucose readily available for substrate. That’s why keto is a
miracle.” (29:34)


“It’s a beautiful thing in terms of evolution that we could be by
the ocean, we could be in the trees, we could be in a barren
winter wasteland, we could be in whatever climate all over the
world and find a food source. That’s incredible.” (46:53)


“When we’re in an optimized state, when our mitochondria are
functioning optimally, we’re not only anti-aging, anti-disease,
pro-energy, but we’re able to deal with stress better.” (1:01:08)


“I think happiness is a choice. Every day you can choose whether
you’re happy or not, whether you’re positive or not.” (1:04:24)


“I have amazing people like you [Dr. Stephanie] in my life
because of the energy I’m putting out is coming back to me. And,
it’s so important that yes you’ve been burned, yes you’ve been
hurt, but don’t let that change what’s going out because that’s
what’s going to come back.” (1:12:44)


“Whatever you’re thinking right now is your weakness is actually
probably your superpower. You’re hiding it away and it’s the
thing you’re so blessed for that makes you unique. And, once you
let it out, you’ll become so powerful.” (1:15:28)


LINKS MENTIONED


Better! Website


Dr. Stephanie’s Website


Dr. Stephanie’s Twitter – @dr_stephanie


Dr. Stephanie’s Instagram – @dr.stephanie.estima


Dr. Stephanie on LinkedIn


Shawn’s Website


Shawn’s Instagram – @zonehalo


Shawn’s LinkedIn


Shawn’s Twitter – @ZoneHalo


Shawn’s Facebook


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