World-renowned neuroscientist Dr. Lisa Mosconi takes us on a
profound exploration of menopause. Together with Dr. Stephanie,
she delves into the intricate physiological and neurological
changes that occur during the perimenopausal, menopausal, and
postmenopausal phases.
In this episode, you will learn about the metabolic, vasomotor,
and neurological shifts reshaping women's brains, unravelling the
mysteries behind hot flashes, mood swings, and cognitive
alterations. You will also discover the evolutionary significance
of menopause and the vital roles grandmothers play in human
communities.
From hormone replacement therapy nuances to empowering lifestyle
interventions, this conversation offers invaluable insights for
women navigating this transformative stage of life. Embark on a
journey of understanding and empowerment, and gain a newfound
appreciation for the resilience and adaptability of the female
brain.
Episode Overview:
0:00 Intro/Teaser
5:04 Unveiling the Menopause Brain
15:08 The Neurological Impact of Menopause
34:41 Neuronal Development and Puberty
43:44 Pregnancy Brain Remodeling
51:26 Evolutionary Significance of Menopause
1:03:41 Neurological Changes Post-Menopause
1:04:39 Hormone Replacement Therapy Considerations
1:09:19 Estrogen and Progesterone Considerations
1:11:46 Types of Progestogens and Progestins
1:17:55 Hormone Options for Breast Cancer History
1:20:22 Limitations and Alternatives of Hormone Therapy
1:24:21 Future of Hormones: Designer Estrogens
1:24:33 Lifestyle Modifications and Clinical Trials
1:33:48 Exercise Routines and Preferences
1:34:58 Importance of Greens and Nutrients
1:39:20 Stress Reduction and Hormonal Balance
Bio:
Lisa Mosconi, PhD, is an associate professor of neuroscience in
neurology and radiology at Weill Cornell Medicine and the
director of the Women’s Brain Initiative and the Alzheimer’s
Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian
Hospital. A world-renowned neuroscientist with a PhD in
neuroscience and nuclear medicine from the University of Florence
in Italy, Mosconi was listed as one of the seventeen most
influential living female scientists by The Times and called “the
Mona Lisa of Neuroscience” by ELLE International. She is the New
York Times bestselling author of The XX Brain and Brain Food.
Website URL: https://www.lisamosconi.com/
Resources mentioned:
The Menopause Brain book -
https://www.lisamosconi.com/the-menopause-brain
Menopause impacts human brain structure, connectivity, energy
metabolism, and amyloid-beta deposition -
https://pubmed.ncbi.nlm.nih.gov/34108509/
Association of reproductive history with brain MRI biomarkers of
dementia risk in midlife -
https://pubmed.ncbi.nlm.nih.gov/34732544/
More research - https://www.lisamosconi.com/research
Women’s Brain Initiative -
https://neurology.weill.cornell.edu/research/womens-brain-initiative
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P.S. When you're ready, here are two ways Dr. Stephanie can help
you:
Subscribe: The Mini
Pause — My weekly newsletter packed with the most
actionable, evidence-based tools for women 40+ to thrive in
midlife.
Build Muscle: LIFT — My
progressive strength training program designed for women in
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