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#133 – Manolis Kellis: Biology of Disease

#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast vor 5 Jahren

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors: - SEMrush: https://www.semrush.com/partner/lex/ to get a free month of Guru - Pessimists Archive: https://pessimists.co/

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2:40:24

Manolis Kellis is a computational biologist at MIT. Please
support this podcast by checking out our sponsors:

– SEMrush: https://www.semrush.com/partner/lex/ to get a
free month of Guru

– Pessimists Archive: https://pessimists.co/

– Eight Sleep: https://www.eightsleep.com/lex and use code
LEX to get $200 off

– BetterHelp: https://betterhelp.com/lex to get 10% off

EPISODE LINKS:

Manolis Website: http://web.mit.edu/manoli/

Manolis Twitter: https://twitter.com/manoliskellis

Manolis YouTube:
https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA

Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis

PODCAST INFO:

Podcast website: https://lexfridman.com/podcast

Apple Podcasts: https://apple.co/2lwqZIr

Spotify: https://spoti.fi/2nEwCF8

RSS: https://lexfridman.com/feed/podcast/

YouTube Full Episodes: https://youtube.com/lexfridman

YouTube Clips: https://youtube.com/lexclips

SUPPORT & CONNECT:

– Check out the sponsors above, it’s the best way to support this
podcast

– Support on Patreon: https://www.patreon.com/lexfridman

– Twitter: https://twitter.com/lexfridman

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– Medium: https://medium.com/@lexfridman

OUTLINE:

Here’s the timestamps for the episode. On some podcast players
you should be able to click the timestamp to jump to that
time.

00:00 – Introduction

08:05 – Molecular basis for human disease

32:04 – Deadliest diseases

37:47 – Genetic component of diseases

46:38 – Genetic understanding of disease

1:02:25 – Unified theory of human disease

1:08:26 – Genome circuitry

1:33:29 – CRISPR

1:45:06 – Mitochondria

1:53:10 – Future of biology research

2:22:46 – The genetic circuitry of disease