podcast.de
Anmeldung
Anmeldung Registrierung
Auto Hell Dunkel
Erweiterte Suche
  1. Startseite
  2. Podcasts
  3. Medizin - Open Access LMU - Teil 14/22 Podcast
  4. Ultrasound mapping of lymph node and subcutaneous metastases in patients with cutaneous melanoma: Results of a prospective multicenter study
Background: Ultrasound (sonography, B-mode sonography,
ultrasonography) examination improves the sensitivity in more than
25% compared to the clinical palpation, especially after surgery on
the regional lymph node area. Objective: To evaluate the
distribution of metastases during follow-up in the draining lymph
node areas from the scar of primary to regional lymph nodes ( head
and neck, supraclavicular, axilla, infraclavicular, groin) in
patients with cutaneous melanoma with or without sentinel lymph
node biopsy (SLNB) or former elective or consecutive complete lymph
node dissection in case of positive sentinel lymph node (CLND).
Methods: Prospective multicenter study of the Departments of
Dermatology of the Universities of Homburg/Saar, Tubingen and
Munich (Germany) in which the distribution of lymph node and
subcutaneous metastases were mapped from the scar of primary to the
lymphatic drainage region in 53 melanoma patients ( 23 women, 30
men; median age: 64 years; median tumor thickness: 1.99 mm) with
known primary, visible lymph nodes or subcutaneous metastases
proven by ultrasound and histopathology during the follow-up.
Results: Especially in the axilla, infraclavicular region and groin
the metastases were not limited to the anatomic lymph node regions.
In 5 patients (9.4%) ( 4 of them were in stage IV) lymph node
metastases were not located in the corresponding lymph node area.
32 patients without former SLNB had a time range between melanoma
excision and lymph node metastases of 31 months ( median), 21
patients with SLNB had 18 months ( p < 0.005). In 11 patients
with positive SLNB the time range was 17 months, in 10 patients
with negative SLNB 21 months ( p < 0.005); in 32 patients with
CLND the time range was 31 m< 0.005). In thinner melanomas lymph
node metastases occurred later ( p < 0.05). Conclusions: After
surgery of cutaneous melanoma, SLNB and CLND the lymphatic drainage
can show significant changes which should be considered in clinical
and ultrasound follow-up examinations. Especially for high-risk
melanoma patients follow-up examinations should be performed at
intervals of 3 months in the first years. Patients at stage IV
should be examined in all regional lymph node areas clinically and
by ultrasound. Copyright (c) 2006 S. Karger AG, Basel.

Weitere Episoden

External quality assessment of urinary methylmalonic acid quantification - results of a pilot study

External quality assessment of urinary methylmalonic acid quantification - results of a pilot study

vor 19 Jahren
Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell turnours

Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell turnours

vor 19 Jahren
Free serum cortisol: quantification applying equilibrium dialysis or ultrafiltration and an automated immunoassay system

Free serum cortisol: quantification applying equilibrium dialysis or ultrafiltration and an automated immunoassay system

vor 19 Jahren
Die Biegestabprothese: ein experimenteller Ansatz zur metaphysären Hüftendoprothetik

Die Biegestabprothese: ein experimenteller Ansatz zur metaphysären Hüftendoprothetik

vor 19 Jahren
ASCO 2007: What remains important for breast cancer systemic therapy in the routine setting?

ASCO 2007: What remains important for breast cancer systemic therapy in the routine setting?

vor 19 Jahren
Alle Episoden anzeigen
In Podcasts werben
Schalte jetzt Werbung in Podcasts.
Episode melden

„Ultrasound mapping of lymph node and subcutaneous metastases in patients with cutaneous melanoma: Results of a prospective multicenter study“

Worum geht es? Danach fragen wir noch nach dem Grund.

Abonnenten

Teilen

Mein Archiv

Deine Privatkopie der Folgen, die du nicht verlieren willst.

Podcast-Folgen verschwinden. Feeds werden auf die letzten Episoden gekürzt, Hoster räumen alte Dateien ab, Formate wechseln den Anbieter und lassen ihr Archiv zurück. Mit „Mein Archiv“ sichert podcast.de die Folgen deiner Podcasts für dich — angefangen bei den ältesten, denn die sind zuerst weg.

  • Deine gesicherten Folgen bleiben hörbar, auch wenn das Original offline geht.
  • Auch Folgen, die im heutigen Feed gar nicht mehr stehen — podcast.de kennt sie noch.
  • Herunterladen bleibt möglich, solange die Folge beim Podcaster liegt. Der zählt seine Abrufe wie bisher.
Startet bald

Sei beim Start von Mein Archiv dabei

Mein Archiv ist fast fertig. Trag dich ein, dann bekommst du eine E-Mail, sobald es losgeht – und bist von Anfang an dabei. Wir schreiben dir nur zum Start, keine Werbung, keine Weitergabe deiner Daten.

Du bekommst zuerst eine Bestätigungsmail. Abmelden geht jederzeit. Datenschutz