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Medizin - Open Access LMU - Teil 09/22 Podcast
The Role of Bile in the Regulation of Exocrine Pancreatic Secretion

The Role of Bile in the Regulation of Exocrine Pancreatic Secretion

Medizin - Open Access LMU - Teil 09/22 vor 34 Jahren

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As early as 1926 Mellanby (1) was able to show that introduction of
bile into the duodenum of anesthetized cats produces a copious flow
of pancreatic juice. In conscious dogs, Ivy & Lueth (2)
reported, bile is only a weak stimulant of pancreatic secretion.
Diversion of bile from the duodenum, however, did not influence
pancreatic volume secretion stimulated by a meal (3,4). Moreover,
Thomas & Crider (5) observed that bile not only failed to
stimulate the secretion of pancreatic juice but also abolished the
pancreatic response to intraduodenally administered peptone or
soap.