podcast.de
Anmeldung
Anmeldung Registrierung
Auto Hell Dunkel
Erweiterte Suche
  1. Startseite
  2. Podcasts
  3. Medizin - Open Access LMU - Teil 17/22 Podcast
  4. Bone metastases from renal cell carcinoma: patient survival after surgical treatment
Background: Surgery is the primary treatment of skeletal metastases
from renal cell carcinoma, because radiation and chemotherapy
frequently are not effecting the survival. We therefore explored
factors potentially affecting the survival of patients after
surgical treatment. Methods: We retrospectively reviewed 101
patients operatively treated for skeletal metastases of renal cell
carcinoma between 1980 and 2005. Overall survival was calculated
using the Kaplan-Meier method. The effects of different variables
were evaluated using a log-rank test. Results: 27 patients had a
solitary bone metastasis, 20 patients multiple bone metastases and
54 patients had concomitant visceral metastases. The overall
survival was 58% at 1 year, 37% at 2 years and 12% at 5 years.
Patients with solitary bone metastases had a better survival (p
< 0.001) compared to patients with multiple metastases. Age
younger than 65 years (p = 0.036), absence of pathologic fractures
(p < 0.001) and tumor-free resection margins (p = 0.028)
predicted higher survival. Gender, location of metastases, time
between diagnosis of renal cell carcinoma and treatment of
metastatic disease, incidence of local recurrence, radiation and
chemotherapy did not influence survival. Conclusions: The data
suggest that patients with a solitary metastasis or a limited
number of resectable metastases are candidates for wide resections.
As radiation and chemotherapy are ineffective in most patients,
surgery is a better option to achieve local tumor control and
increase the survival.

Weitere Episoden

Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis

Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis

vor 15 Jahren
Biliary Bicarbonate Secretion Constitutes a Protective Mechanism against Bile Acid-Induced Injury in Man

Biliary Bicarbonate Secretion Constitutes a Protective Mechanism against Bile Acid-Induced Injury in Man

vor 15 Jahren
Growth Pattern of Untreated Boys with Simple Virilizing Congenital Adrenal Hyperplasia Indicates Relative Androgen Insensitivity during the First Six Months of Life

Growth Pattern of Untreated Boys with Simple Virilizing Congenital Adrenal Hyperplasia Indicates Relative Androgen Insensitivity during the First Six Months of Life

vor 15 Jahren
Growth Patterns in the First Three Years of Life in Children with Classical Congenital Adrenal Hyperplasia Diagnosed by Newborn Screening and Treated with Low Doses of Hydrocortisone

Growth Patterns in the First Three Years of Life in Children with Classical Congenital Adrenal Hyperplasia Diagnosed by Newborn Screening and Treated with Low Doses of Hydrocortisone

vor 15 Jahren
Missing Heritability in the Tails of Quantitative Traits? A Simulation Study on the Impact of Slightly Altered True Genetic Models

Missing Heritability in the Tails of Quantitative Traits? A Simulation Study on the Impact of Slightly Altered True Genetic Models

vor 15 Jahren
Alle Episoden anzeigen
In Podcasts werben
Schalte jetzt Werbung in Podcasts.
Episode melden

„Bone metastases from renal cell carcinoma: patient survival after surgical treatment“

Worum geht es? Danach fragen wir noch nach dem Grund.

Abonnenten

Er
Erasmus2

Teilen

Mein Archiv

Deine Privatkopie der Folgen, die du nicht verlieren willst.

Podcast-Folgen verschwinden. Feeds werden auf die letzten Episoden gekürzt, Hoster räumen alte Dateien ab, Formate wechseln den Anbieter und lassen ihr Archiv zurück. Mit „Mein Archiv“ sichert podcast.de die Folgen deiner Podcasts für dich — angefangen bei den ältesten, denn die sind zuerst weg.

  • Deine gesicherten Folgen bleiben hörbar, auch wenn das Original offline geht.
  • Auch Folgen, die im heutigen Feed gar nicht mehr stehen — podcast.de kennt sie noch.
  • Herunterladen bleibt möglich, solange die Folge beim Podcaster liegt. Der zählt seine Abrufe wie bisher.
Startet bald

Sei beim Start von Mein Archiv dabei

Mein Archiv ist fast fertig. Trag dich ein, dann bekommst du eine E-Mail, sobald es losgeht – und bist von Anfang an dabei. Wir schreiben dir nur zum Start, keine Werbung, keine Weitergabe deiner Daten.

Du bekommst zuerst eine Bestätigungsmail. Abmelden geht jederzeit. Datenschutz