Der Effekt UV-blockierender Kontaktlinsen bei der Therapie der Keratitis superficialis chronica des Hundes

Objective Canine chronic superficial keratitis (CSK) is chronic,
progressive keratopathy, which is suspected to be caused by an
immune mediated response triggered by ultraviolet light exposure.
The purpose of this study was to evaluate the effect of UV-blocking
soft contact lenses in treatment for CSK. Methods 26 dogs (26 eyes)
with CSK were treated continuously with UV-blocking contact lenses
(*Acri.Pat-UV bandage lenses) for six months. A contact lens was
placed on one eye of each dog; the other eye remained without a
lens as a control eye. Then, five dogs were treated further on
wearing now contact lenses on either eye. Continuously, all
patients were treated topically with cyclosporine A on both eyes.
The contact lenses were changed every four weeks and an ophthalmic
examination was performed at each appointment. Evaluation criteria
included corneal alterations as pigmentation, edema, pannus and
vascularisation based on digital photographs and drawings. To
determine the transmittance characteristics of the contact lenses
before and after use, 32 contact lenses were measured with a
UV-vis-NIR spectrophotometer. Results Pigmentation increased in
eyes wearing contact lenses and in control eyes over the evaluation
period of six months. Corneal edema increased in the eyes wearing
lenses, but remained unaffected in the control eyes. A significant
difference in the incidence of pannus and the extent of corneal
vascularisation could not be evaluated. Side effects were noted in
six cases (corneal edema and vascularisation, conjunctivitis,
blepharospasm). All new lenses studied reduced UV-radiation to a
safe level, whereas used lenses did not maintain their
transmittance characteristics. Conclusion Extended wear of
UV-blocking contact lenses is an ineffective treatment for canine
CSK and bears the risk of severe side effects