Der Einfluss der alimentären Phosphorversorgung auf ausgewählte Nierenfunktionsparameter bei Katzen

In the present investigation the influence of a constant level of P
excess (890 mg/MJ ME) was examined in 20 European shorthair cats
using the following study design: 1.) a Ca/P-ratio in the
recommended range (1.3:1) 2.) an inverse Ca/P ratio (0.4:1)
according to Pastoor (1993) and 3.) a high Na and marginal K supply
as well as an inverse Ca/P-ratio (0.4:1). Selected parameters of
renal health including endogenous creatinine clearance, serum
chemistry, urine analysis as well as faecal and renal mineral
excretion were determined. In both trials with inverse Ca/P-ratio
the endogenous creatinine clearance was significantly reduced and
therefore confirmed the findings of Pastoor (1993). Furthermore,
renal protein and glucose excretion increased. All effects were
aggravated by multiple inappropriate mineral supply (Na excess and
marginal K supply). Feeding the P excess diet with balanced Ca
supply (Ca/P=1.3:1) for the limited study period of 28 days did not
lead to comparably altered clinical findings. Possible long-term
effects under these conditions can not be assessed on the basis of
the current results.