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A large fraction of murine tumors induced by transgenic expression
of SV40 large T antigen (SV40 TAg) exhibits a neuroendocrine
phenotype. It is unclear whether SV40 TAg induces the
neuroendocrine phenotype by preferential transformation of
progenito...
Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor
antagonist that is administered to treat Menière's disease. Despite
widespread use, its pharmacological mode of action has not been
entirely elucidated. This study investigated the ef...
01.01.2012
Red blood cell (RBC) n-3 fatty acid status is related to various
health outcomes. Accepted biological markers for the fatty acid
status determination are RBC phospholipids, phosphatidylcholine,
and phosphatidyletholamine. The analysis of these lipid...
Thus, we evaluated the immunofluorescence pattern of
TRAIL-receptors and E-cadherin to assess the fraction of
membrane-bound TRAIL-receptors in 231 selected patients with
early-stage CRC undergoing surgical treatment only. Moreover, we
investigated w...
01.01.2012
The goal of the present study was to determine whether treatment
with cigarette smoke extract (CSE) induces cell loss, cellular
senescence, and extracellular matrix (ECM) synthesis in primary
human retinal pigment epithelial (RPE) cells. Primary cult...
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