Immunsuppressiva-Medikamentenspiegelmessung – reine Routine? / Immunosuppressant drug monitoring – a routine undertaking? 2/2

The quantitative assessment of immunosuppressant drug levels is
still one of the most challenging therapeutic drug monitoring
procedures in clinical routine. During the past years, several
technical developments matured to useable methods. In addition to
immunoassays, liquid chromatography- tandem mass spectrometry has
become a key method in immunosuppressant therapeutic drug
monitoring. This overview should aid in understanding the
advantages and disadvantages of the various assays and methods.
UKNEQAS proficiency testing results are used for an inter-assay
comparison approach.