Quality of life in the follow-up of uveal melanoma patients after CyberKnife treatment

To assess quality of life in uveal melanoma patients within the
first and second year after CyberKnife radiosurgery. Overall, 91
uveal melanoma patients were evaluated for quality of life through
the Short-form (SF-12) Health Survey at baseline and at every
follow-up visit over 2 years after CyberKnife radiosurgery.
Statistical analysis was carried out using SF Health Outcomes
Scoring Software and included subgroup analysis of patients
developing secondary glaucoma and of patients maintaining a best
corrected visual acuity (BCVA) of the treated eye of 0.5 log(MAR)
or better. Analysis of variance, Greenhouse-Geisser correction,
Student's t-test, and Fisher's exact test were used to determine
statistical significance. Physical Functioning (PF) and Role
Physical (RP) showed a significant decrease after CyberKnife
radiosurgery, whereas Mental Health (MH) improved (P=0.007,
P